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Current spectrum of causative pathogens in sepsis: A prospective nationwide cohort study in Japan.
Umemura Y, Ogura H, Takuma K, Fujishima S, Abe T, Kushimoto S, Hifumi T, Hagiwara A, Shiraishi A, Otomo Y, Saitoh D, Mayumi T, Yamakawa K, Shiino Y, Nakada TA, Tarui T, Okamoto K, Kotani J, Sakamoto Y, Sasaki J, Shiraishi SI, Tsuruta R, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Gando S; Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome Sepsis and Trauma (FORECAST) Study Group. Umemura Y, et al. Int J Infect Dis. 2021 Feb;103:343-351. doi: 10.1016/j.ijid.2020.11.168. Epub 2020 Nov 19. Int J Infect Dis. 2021. PMID: 33221519 Free article.
BACKGROUND: There is no one-size-fits-all empiric antimicrobial therapy for sepsis because the pathogens vary according to the site of infection and have changed over time. ...OBJECTIVE: The aim of this study was to elucidate the current spectrum of pathogens and its varia …
BACKGROUND: There is no one-size-fits-all empiric antimicrobial therapy for sepsis because the pathogens vary according to the site o …
Hyperoxemia during resuscitation of trauma patients and increased intensive care unit length of stay: inverse probability of treatment weighting analysis.
Yamamoto R, Fujishima S, Sasaki J, Gando S, Saitoh D, Shiraishi A, Kushimoto S, Ogura H, Abe T, Mayumi T, Kotani J, Nakada TA, Shiino Y, Tarui T, Okamoto K, Sakamoto Y, Shiraishi SI, Takuma K, Tsuruta R, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Hifumi T, Yamakawa K, Hagiwara A, Otomo Y; Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis and Trauma (FORECAST) Study Group. Yamamoto R, et al. World J Emerg Surg. 2021 Apr 29;16(1):19. doi: 10.1186/s13017-021-00363-2. World J Emerg Surg. 2021. PMID: 33926507 Free PMC article.
BACKGROUND: Information on hyperoxemia among patients with trauma has been limited, other than traumatic brain injuries. This study aimed to elucidate whether hyperoxemia during resuscitation of patients with trauma was associated with unfavorable o …
BACKGROUND: Information on hyperoxemia among patients with trauma has been limited, other than traumatic brain injuries. This …
Role of disseminated intravascular coagulation in severe sepsis.
Gando S, Shiraishi A, Yamakawa K, Ogura H, Saitoh D, Fujishima S, Mayumi T, Kushimoto S, Abe T, Shiino Y, Nakada TA, Tarui T, Hifumi T, Otomo Y, Okamoto K, Umemura Y, Kotani J, Sakamoto Y, Sasaki J, Shiraishi SI, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S; Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis and Trauma (FORECAST) Study Group. Gando S, et al. Thromb Res. 2019 Jun;178:182-188. doi: 10.1016/j.thromres.2019.04.025. Epub 2019 Apr 26. Thromb Res. 2019. PMID: 31054468
BACKGROUND: Disseminated intravascular coagulation (DIC) associated with multiple organ dysfunction syndrome (MODS) plays pivotal roles in severe sepsis. ...DIC scores as well as disease severity and the development of MODS on the day of the diagnosis of seve …
BACKGROUND: Disseminated intravascular coagulation (DIC) associated with multiple organ dysfunction syndrome (MODS) plays pivo …
The significance of disseminated intravascular coagulation on multiple organ dysfunction during the early stage of acute respiratory distress syndrome.
Gando S, Fujishima S, Saitoh D, Shiraishi A, Yamakawa K, Kushimoto S, Ogura H, Abe T, Mayumi T, Sasaki J, Kotani J, Takeyama N, Tsuruta R, Takuma K, Yamashita N, Shiraishi SI, Ikeda H, Shiino Y, Tarui T, Nakada TA, Hifumi T, Otomo Y, Okamoto K, Sakamoto Y, Hagiwara A, Masuno T, Ueyama M, Fujimi S, Umemura Y; Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis and Trauma (FORECAST) Study Group. Gando S, et al. Thromb Res. 2020 Jul;191:15-21. doi: 10.1016/j.thromres.2020.03.023. Epub 2020 Apr 18. Thromb Res. 2020. PMID: 32353745
BACKGROUND: Multiple organ dysfunction syndrome (MODS) is a predominant cause of death in acute respiratory distress syndrome (ARDS). ...CONCLUSIONS: DIC scores were able to predict MODS, and DIC was associated with MODS during the early …
BACKGROUND: Multiple organ dysfunction syndrome (MODS) is a predominant cause of death in acute respiratory distress …
Identifying Sepsis Populations Benefitting from Anticoagulant Therapy: A Prospective Cohort Study Incorporating a Restricted Cubic Spline Regression Model.
Yamakawa K, Gando S, Ogura H, Umemura Y, Kabata D, Shintani A, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Kushimoto S, Abe T, Shiino Y, Nakada TA, Tarui T, Hifumi T, Otomo Y, Okamoto K, Kotani J, Sakamoto Y, Sasaki J, Shiraishi SI, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S; Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis Trauma (FORECAST) Study Group. Yamakawa K, et al. Thromb Haemost. 2019 Nov;119(11):1740-1751. doi: 10.1055/s-0039-1693740. Epub 2019 Aug 13. Thromb Haemost. 2019. PMID: 31408900
OBJECTIVE: This article identifies the optimal target of anticoagulant therapy in sepsis. METHODS: We used a prospective nationwide cohort targeting consecutive adult severe sepsis patients in 59 intensive care units in Japan to assess associations bet …
OBJECTIVE: This article identifies the optimal target of anticoagulant therapy in sepsis. METHODS: We used a prospective nationwide c …
Identifying Septic Shock Populations Benefitting From Polymyxin B Hemoperfusion: A Prospective Cohort Study Incorporating a Restricted Cubic Spline Regression Model.
Nakata H, Yamakawa K, Kabata D, Umemura Y, Ogura H, Gando S, Shintani A, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Kushimoto S, Abe T, Shiino Y, Nakada TA, Tarui T, Hifumi T, Otomo Y, Okamoto K, Kotani J, Sakamoto Y, Sasaki J, Shiraishi SI, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Fujimi S; Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis and Trauma (FORECAST) Study Group. Nakata H, et al. Shock. 2020 Nov;54(5):667-674. doi: 10.1097/SHK.0000000000001533. Shock. 2020. PMID: 32195922 Clinical Trial.
METHODS: We used a prospective nationwide cohort targeting consecutive adult patients with severe sepsis (Sepsis-2) in 59 intensive care units in Japan. Associations between PMX-HP therapy and in-hospital mortality were assessed using multivariable Cox …
METHODS: We used a prospective nationwide cohort targeting consecutive adult patients with severe sepsis (Sepsis-2) in 59 inte …
Prognostic Accuracy of Quick SOFA is different according to the severity of illness in infectious patients.
Umemura Y, Ogura H, Gando S, Shiraishi A, Saitoh D, Fujishima S, Mayumi T, Kushimoto S, Abe T, Shiino Y, Nakada TA, Tarui T, Hifumi T, Otomo Y, Okamoto K, Kotani J, Sakamoto Y, Sasaki J, Shiraishi SI, Takuma K, Tsuruta R, Hagiwara A, Masuno T, Takeyama N, Yamashita N, Ikeda H, Ueyama M, Yamakawa K; Japanese Association for Acute Medicine (JAAM) Focused Outcomes Research in Emergency Care in Acute Respiratory Distress Syndrome, Sepsis and Trauma (FORECAST) Study Group. Umemura Y, et al. J Infect Chemother. 2019 Dec;25(12):943-949. doi: 10.1016/j.jiac.2019.05.010. Epub 2019 Jun 8. J Infect Chemother. 2019. PMID: 31182332
BACKGROUND: Sepsis-3 proposed the quick Sequential Organ Failure Assessment (qSOFA) to identify sepsis patients likely to have poor outcome. ...MATERIALS AND METHODS: This was a post hoc analysis of a prospective nationwide cohort of consecutive adult …
BACKGROUND: Sepsis-3 proposed the quick Sequential Organ Failure Assessment (qSOFA) to identify sepsis patients likely …