Janssens V - Search Results

1

Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis.

Elgendy M, Cirò M, Hosseini A, Weiszmann J, Mazzarella L, Ferrari E, Cazzoli R, Curigliano G, DeCensi A, Bonanni B, Budillon A, Pelicci PG, Janssens V, Ogris M, Baccarini M, Lanfrancone L, Weckwerth W, Foiani M, Minucci S. Elgendy M, et al. Among authors: janssens v. Cancer Cell. 2019 May 13;35(5):798-815.e5. doi: 10.1016/j.ccell.2019.03.007. Epub 2019 Apr 25. Cancer Cell. 2019. PMID: 31031016 Free article.

2

Recurrent PPP2R1A Mutations in Uterine Cancer Act through a Dominant-Negative Mechanism to Promote Malignant Cell Growth.

Haesen D, Abbasi Asbagh L, Derua R, Hubert A, Schrauwen S, Hoorne Y, Amant F, Waelkens E, Sablina A, Janssens V. Haesen D, et al. Among authors: janssens v. Cancer Res. 2016 Oct 1;76(19):5719-5731. doi: 10.1158/0008-5472.CAN-15-3342. Epub 2016 Aug 2. Cancer Res. 2016. PMID: 27485451

3

PPP2R4 dysfunction promotes KRAS-mutant lung adenocarcinoma development and mediates opposite responses to MEK and mTOR inhibition.

Meeusen B, Cortesi EE, Domènech Omella J, Sablina A, Ventura JJ, Janssens V. Meeusen B, et al. Among authors: janssens v. Cancer Lett. 2021 Nov 1;520:57-67. doi: 10.1016/j.canlet.2021.06.022. Epub 2021 Jun 30. Cancer Lett. 2021. PMID: 34216687

4

Mice lacking phosphatase PP2A subunit PR61/B'delta (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3beta.

Louis JV, Martens E, Borghgraef P, Lambrecht C, Sents W, Longin S, Zwaenepoel K, Pijnenborg R, Landrieu I, Lippens G, Ledermann B, Götz J, Van Leuven F, Goris J, Janssens V. Louis JV, et al. Among authors: janssens v. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6957-62. doi: 10.1073/pnas.1018777108. Epub 2011 Apr 11. Proc Natl Acad Sci U S A. 2011. PMID: 21482799 Free PMC article.

5

Glucose-induced posttranslational activation of protein phosphatases PP2A and PP1 in yeast.

Castermans D, Somers I, Kriel J, Louwet W, Wera S, Versele M, Janssens V, Thevelein JM. Castermans D, et al. Among authors: janssens v. Cell Res. 2012 Jun;22(6):1058-77. doi: 10.1038/cr.2012.20. Epub 2012 Jan 31. Cell Res. 2012. PMID: 22290422 Free PMC article.

6

Structure, regulation, and pharmacological modulation of PP2A phosphatases.

Lambrecht C, Haesen D, Sents W, Ivanova E, Janssens V. Lambrecht C, et al. Among authors: janssens v. Methods Mol Biol. 2013;1053:283-305. doi: 10.1007/978-1-62703-562-0_17. Methods Mol Biol. 2013. PMID: 23860660 Review.

7

PP2A binds to the LIM domains of lipoma-preferred partner through its PR130/B″ subunit to regulate cell adhesion and migration.

Janssens V, Zwaenepoel K, Rossé C, Petit MM, Goris J, Parker PJ. Janssens V, et al. J Cell Sci. 2016 Apr 15;129(8):1605-18. doi: 10.1242/jcs.175778. Epub 2016 Mar 4. J Cell Sci. 2016. PMID: 26945059 Free PMC article.

8

Loss of protein phosphatase 2A regulatory subunit B56δ promotes spontaneous tumorigenesis in vivo.

Lambrecht C, Libbrecht L, Sagaert X, Pauwels P, Hoorne Y, Crowther J, Louis JV, Sents W, Sablina A, Janssens V. Lambrecht C, et al. Among authors: janssens v. Oncogene. 2018 Jan 25;37(4):544-552. doi: 10.1038/onc.2017.350. Epub 2017 Oct 2. Oncogene. 2018. PMID: 28967903

9

Tumor suppressive protein phosphatases in human cancer: Emerging targets for therapeutic intervention and tumor stratification.

Meeusen B, Janssens V. Meeusen B, et al. Among authors: janssens v. Int J Biochem Cell Biol. 2018 Mar;96:98-134. doi: 10.1016/j.biocel.2017.10.002. Epub 2017 Oct 12. Int J Biochem Cell Biol. 2018. PMID: 29031806 Review.

10

PP2A Inactivation Mediated by PPP2R4 Haploinsufficiency Promotes Cancer Development.

Sents W, Meeusen B, Kalev P, Radaelli E, Sagaert X, Miermans E, Haesen D, Lambrecht C, Dewerchin M, Carmeliet P, Westermarck J, Sablina A, Janssens V. Sents W, et al. Among authors: janssens v. Cancer Res. 2017 Dec 15;77(24):6825-6837. doi: 10.1158/0008-5472.CAN-16-2911. Epub 2017 Oct 18. Cancer Res. 2017. PMID: 29046336

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