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Combination of common mtDNA variants results in mitochondrial dysfunction and a connective tissue dysregulation.
Schaefer PM, Scherer Alves L, Lvova M, Huang J, Rathi K, Janssen K, Butic A, Yardeni T, Morrow R, Lott M, Murdock D, Song A, Keller K, Garcia BA, Francomano CA, Wallace DC. Schaefer PM, et al. Among authors: janssen k. Proc Natl Acad Sci U S A. 2022 Nov 8;119(45):e2212417119. doi: 10.1073/pnas.2212417119. Epub 2022 Nov 2. Proc Natl Acad Sci U S A. 2022. PMID: 36322731 Free PMC article.
Regulation of nuclear epigenome by mitochondrial DNA heteroplasmy.
Kopinski PK, Janssen KA, Schaefer PM, Trefely S, Perry CE, Potluri P, Tintos-Hernandez JA, Singh LN, Karch KR, Campbell SL, Doan MT, Jiang H, Nissim I, Nakamaru-Ogiso E, Wellen KE, Snyder NW, Garcia BA, Wallace DC. Kopinski PK, et al. Among authors: janssen ka. Proc Natl Acad Sci U S A. 2019 Aug 6;116(32):16028-16035. doi: 10.1073/pnas.1906896116. Epub 2019 Jun 28. Proc Natl Acad Sci U S A. 2019. PMID: 31253706 Free PMC article.
TET2 chemically modifies tRNAs and regulates tRNA fragment levels.
He C, Bozler J, Janssen KA, Wilusz JE, Garcia BA, Schorn AJ, Bonasio R. He C, et al. Nat Struct Mol Biol. 2021 Jan;28(1):62-70. doi: 10.1038/s41594-020-00526-w. Epub 2020 Nov 23. Nat Struct Mol Biol. 2021. PMID: 33230319 Free PMC article.
499 results