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Defective transcription elongation in a subset of cancers confers immunotherapy resistance.
Modur V, Singh N, Mohanty V, Chung E, Muhammad B, Choi K, Chen X, Chetal K, Ratner N, Salomonis N, Weirauch MT, Waltz S, Huang G, Privette-Vinnedge L, Park JS, Janssen EM, Komurov K. Modur V, et al. Among authors: janssen em. Nat Commun. 2018 Oct 23;9(1):4410. doi: 10.1038/s41467-018-06810-0. Nat Commun. 2018. PMID: 30353012 Free PMC article.
PD1 blockade enhances K+ channel activity, Ca2+ signaling, and migratory ability in cytotoxic T lymphocytes of patients with head and neck cancer.
Newton HS, Gawali VS, Chimote AA, Lehn MA, Palackdharry SM, Hinrichs BH, Jandarov R, Hildeman D, Janssen EM, Wise-Draper TM, Conforti L. Newton HS, et al. Among authors: janssen em. J Immunother Cancer. 2020 Oct;8(2):e000844. doi: 10.1136/jitc-2020-000844. J Immunother Cancer. 2020. PMID: 33060146 Free PMC article.
152 results