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Identification of the allosteric P2X7 receptor antagonist [11C]SMW139 as a PET tracer of microglial activation.
Janssen B, Vugts DJ, Wilkinson SM, Ory D, Chalon S, Hoozemans JJM, Schuit RC, Beaino W, Kooijman EJM, van den Hoek J, Chishty M, Doméné A, Van der Perren A, Villa A, Maggi A, Molenaar GT, Funke U, Shevchenko RV, Baekelandt V, Bormans G, Lammertsma AA, Kassiou M, Windhorst AD. Janssen B, et al. Sci Rep. 2018 Apr 26;8(1):6580. doi: 10.1038/s41598-018-24814-0. Sci Rep. 2018. PMID: 29700413 Free PMC article.
Novel Thienopyrimidine-Based PET Tracers for P2Y12 Receptor Imaging in the Brain.
van der Wildt B, Janssen B, Pekošak A, Stéen EJL, Schuit RC, Kooijman EJM, Beaino W, Vugts DJ, Windhorst AD. van der Wildt B, et al. Among authors: janssen b. ACS Chem Neurosci. 2021 Dec 1;12(23):4465-4474. doi: 10.1021/acschemneuro.1c00641. Epub 2021 Nov 10. ACS Chem Neurosci. 2021. PMID: 34757711 Free PMC article.
Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.
Villa A, Klein B, Janssen B, Pedragosa J, Pepe G, Zinnhardt B, Vugts DJ, Gelosa P, Sironi L, Beaino W, Damont A, Dollé F, Jego B, Winkeler A, Ory D, Solin O, Vercouillie J, Funke U, Laner-Plamberger S, Blomster LV, Christophersen P, Vegeto E, Aigner L, Jacobs A, Planas AM, Maggi A, Windhorst AD. Villa A, et al. Among authors: janssen b. Theranostics. 2018 Oct 27;8(19):5400-5418. doi: 10.7150/thno.25572. eCollection 2018. Theranostics. 2018. PMID: 30555554 Free PMC article.
The P2X7 receptor tracer [11C]SMW139 as an in vivo marker of neuroinflammation in multiple sclerosis: a first-in man study.
Hagens MHJ, Golla SSV, Janssen B, Vugts DJ, Beaino W, Windhorst AD, O'Brien-Brown J, Kassiou M, Schuit RC, Schwarte LA, de Vries HE, Killestein J, Barkhof F, van Berckel BNM, Lammertsma AA. Hagens MHJ, et al. Among authors: janssen b. Eur J Nucl Med Mol Imaging. 2020 Feb;47(2):379-389. doi: 10.1007/s00259-019-04550-x. Epub 2019 Nov 8. Eur J Nucl Med Mol Imaging. 2020. PMID: 31705174 Free PMC article.
603 results