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Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice.
Cimen I, Natarelli L, Abedi Kichi Z, Henderson JM, Farina FM, Briem E, Aslani M, Megens RTA, Jansen Y, Mann-Fallenbuchel E, Gencer S, Duchêne J, Nazari-Jahantigh M, van der Vorst EPC, Enard W, Döring Y, Schober A, Santovito D, Weber C. Cimen I, et al. Among authors: jansen y. Sci Transl Med. 2023 Nov;15(720):eadf3357. doi: 10.1126/scitranslmed.adf3357. Epub 2023 Nov 1. Sci Transl Med. 2023. PMID: 37910599
Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity: Evidence From Mouse and Human Studies.
Döring Y, Noels H, van der Vorst EPC, Neideck C, Egea V, Drechsler M, Mandl M, Pawig L, Jansen Y, Schröder K, Bidzhekov K, Megens RTA, Theelen W, Klinkhammer BM, Boor P, Schurgers L, van Gorp R, Ries C, Kusters PJH, van der Wal A, Hackeng TM, Gäbel G, Brandes RP, Soehnlein O, Lutgens E, Vestweber D, Teupser D, Holdt LM, Rader DJ, Saleheen D, Weber C. Döring Y, et al. Among authors: jansen y. Circulation. 2017 Jul 25;136(4):388-403. doi: 10.1161/CIRCULATIONAHA.117.027646. Epub 2017 Apr 27. Circulation. 2017. PMID: 28450349 Free PMC article.
Adipocyte-Specific ACKR3 Regulates Lipid Levels in Adipose Tissue.
Gencer S, Döring Y, Jansen Y, Bayasgalan S, Schengel O, Müller M, Peters LJF, Weber C, van der Vorst EPC. Gencer S, et al. Among authors: jansen y. Biomedicines. 2021 Apr 6;9(4):394. doi: 10.3390/biomedicines9040394. Biomedicines. 2021. PMID: 33917642 Free PMC article.
Adipocyte calcium sensing receptor is not involved in visceral adipose tissue inflammation or atherosclerosis development in hyperlipidemic Apoe-/- mice.
Sundararaman SS, Peters LJF, Jansen Y, Gencer S, Yan Y, Nazir S, Bonnin Marquez A, Kahles F, Lehrke M, Biessen EAL, Jankowski J, Weber C, Döring Y, van der Vorst EPC. Sundararaman SS, et al. Among authors: jansen y. Sci Rep. 2021 May 17;11(1):10409. doi: 10.1038/s41598-021-89893-y. Sci Rep. 2021. PMID: 34001955 Free PMC article.
Endothelial ACKR3 drives atherosclerosis by promoting immune cell adhesion to vascular endothelium.
Gencer S, Döring Y, Jansen Y, Bayasgalan S, Yan Y, Bianchini M, Cimen I, Müller M, Peters LJF, Megens RTA, von Hundelshausen P, Duchene J, Lemnitzer P, Soehnlein O, Weber C, van der Vorst EPC. Gencer S, et al. Among authors: jansen y. Basic Res Cardiol. 2022 Jun 8;117(1):30. doi: 10.1007/s00395-022-00937-4. Basic Res Cardiol. 2022. PMID: 35674847 Free PMC article.
Hematopoietic ChemR23 (Chemerin Receptor 23) Fuels Atherosclerosis by Sustaining an M1 Macrophage-Phenotype and Guidance of Plasmacytoid Dendritic Cells to Murine Lesions-Brief Report.
van der Vorst EPC, Mandl M, Müller M, Neideck C, Jansen Y, Hristov M, Gencer S, Peters LJF, Meiler S, Feld M, Geiselhöringer AL, de Jong RJ, Ohnmacht C, Noels H, Soehnlein O, Drechsler M, Weber C, Döring Y. van der Vorst EPC, et al. Among authors: jansen y. Arterioscler Thromb Vasc Biol. 2019 Apr;39(4):685-693. doi: 10.1161/ATVBAHA.119.312386. Arterioscler Thromb Vasc Biol. 2019. PMID: 30786742 Free article.
Endothelial ADAM10 controls cellular response to oxLDL and its deficiency exacerbates atherosclerosis with intraplaque hemorrhage and neovascularization in mice.
van der Vorst EPC, Maas SL, Theodorou K, Peters LJF, Jin H, Rademakers T, Gijbels MJ, Rousch M, Jansen Y, Weber C, Lehrke M, Lebherz C, Yildiz D, Ludwig A, Bentzon JF, Biessen EAL, Donners MMPC. van der Vorst EPC, et al. Among authors: jansen y. Front Cardiovasc Med. 2023 Jan 27;10:974918. doi: 10.3389/fcvm.2023.974918. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 36776254 Free PMC article.
The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice.
Kiouptsi K, Jäckel S, Pontarollo G, Grill A, Kuijpers MJE, Wilms E, Weber C, Sommer F, Nagy M, Neideck C, Jansen Y, Ascher S, Formes H, Karwot C, Bayer F, Kollar B, Subramaniam S, Molitor M, Wenzel P, Rosenstiel P, Todorov H, Gerber S, Walter U, Jurk K, Heemskerk JWM, van der Vorst EPC, Döring Y, Reinhardt C. Kiouptsi K, et al. Among authors: jansen y. mBio. 2019 Oct 22;10(5):e02298-19. doi: 10.1128/mBio.02298-19. mBio. 2019. PMID: 31641089 Free PMC article.
83 results