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A common co-morbidity modulates disease expression and treatment efficacy in inherited cardiac sodium channelopathy.
Rivaud MR, Jansen JA, Postema PG, Nannenberg EA, Mizusawa Y, van der Nagel R, Wolswinkel R, van der Made I, Marchal GA, Rajamani S, Belardinelli L, van Tintelen JP, Tanck MWT, van der Wal AC, de Bakker JMT, van Rijen HV, Creemers EE, Wilde AAM, van den Berg MP, van Veen TAB, Bezzina CR, Remme CA. Rivaud MR, et al. Among authors: jansen ja. Eur Heart J. 2018 Aug 14;39(31):2898-2907. doi: 10.1093/eurheartj/ehy247. Eur Heart J. 2018. PMID: 29718149
Functional modulation of atrio-ventricular conduction by enhanced late sodium current and calcium-dependent mechanisms in Scn5a1798insD/+ mice.
Rivaud MR, Marchal GA, Wolswinkel R, Jansen JA, van der Made I, Beekman L, Ruiz-Villalba A, Baartscheer A, Rajamani S, Belardinelli L, van Veen TAB, Basso C, Thiene G, Creemers EE, Bezzina CR, Remme CA. Rivaud MR, et al. Among authors: jansen ja. Europace. 2020 Oct 1;22(10):1579-1589. doi: 10.1093/europace/euaa127. Europace. 2020. PMID: 32778883 Free PMC article.
Dominant arrhythmia vulnerability of the right ventricle in senescent mice.
Stein M, Noorman M, van Veen TA, Herold E, Engelen MA, Boulaksil M, Antoons G, Jansen JA, van Oosterhout MF, Hauer RN, de Bakker JM, van Rijen HV. Stein M, et al. Among authors: jansen ja. Heart Rhythm. 2008 Mar;5(3):438-48. doi: 10.1016/j.hrthm.2007.10.033. Epub 2007 Oct 23. Heart Rhythm. 2008. PMID: 18313604
Cardiac connexins and impulse propagation.
Jansen JA, van Veen TA, de Bakker JM, van Rijen HV. Jansen JA, et al. J Mol Cell Cardiol. 2010 Jan;48(1):76-82. doi: 10.1016/j.yjmcc.2009.08.018. Epub 2009 Aug 31. J Mol Cell Cardiol. 2010. PMID: 19729017 Review.
Reduction of fibrosis-related arrhythmias by chronic renin-angiotensin-aldosterone system inhibitors in an aged mouse model.
Stein M, Boulaksil M, Jansen JA, Herold E, Noorman M, Joles JA, van Veen TA, Houtman MJ, Engelen MA, Hauer RN, de Bakker JM, van Rijen HV. Stein M, et al. Among authors: jansen ja. Am J Physiol Heart Circ Physiol. 2010 Aug;299(2):H310-21. doi: 10.1152/ajpheart.01137.2009. Epub 2010 Apr 30. Am J Physiol Heart Circ Physiol. 2010. PMID: 20435847 Free article.
Heterogeneous Connexin43 distribution in heart failure is associated with dispersed conduction and enhanced susceptibility to ventricular arrhythmias.
Boulaksil M, Winckels SK, Engelen MA, Stein M, van Veen TA, Jansen JA, Linnenbank AC, Bierhuizen MF, Groenewegen WA, van Oosterhout MF, Kirkels JH, de Jonge N, Varró A, Vos MA, de Bakker JM, van Rijen HV. Boulaksil M, et al. Among authors: jansen ja. Eur J Heart Fail. 2010 Sep;12(9):913-21. doi: 10.1093/eurjhf/hfq092. Epub 2010 Jun 9. Eur J Heart Fail. 2010. PMID: 20534605 Free article.
Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice.
Jansen JA, Noorman M, Musa H, Stein M, de Jong S, van der Nagel R, Hund TJ, Mohler PJ, Vos MA, van Veen TA, de Bakker JM, Delmar M, van Rijen HV. Jansen JA, et al. Heart Rhythm. 2012 Apr;9(4):600-7. doi: 10.1016/j.hrthm.2011.11.025. Epub 2011 Nov 16. Heart Rhythm. 2012. PMID: 22100711 Free PMC article.
Reduced Cx43 expression triggers increased fibrosis due to enhanced fibroblast activity.
Jansen JA, van Veen TA, de Jong S, van der Nagel R, van Stuijvenberg L, Driessen H, Labzowski R, Oefner CM, Bosch AA, Nguyen TQ, Goldschmeding R, Vos MA, de Bakker JM, van Rijen HV. Jansen JA, et al. Circ Arrhythm Electrophysiol. 2012 Apr;5(2):380-90. doi: 10.1161/CIRCEP.111.966580. Epub 2012 Feb 24. Circ Arrhythm Electrophysiol. 2012. PMID: 22368123
768 results