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Page 1
Broader Epstein-Barr virus-specific T cell receptor repertoire in patients with multiple sclerosis.
Schneider-Hohendorf T, Gerdes LA, Pignolet B, Gittelman R, Ostkamp P, Rubelt F, Raposo C, Tackenberg B, Riepenhausen M, Janoschka C, Wünsch C, Bucciarelli F, Flierl-Hecht A, Beltrán E, Kümpfel T, Anslinger K, Gross CC, Chapman H, Kaplan I, Brassat D, Wekerle H, Kerschensteiner M, Klotz L, Lünemann JD, Hohlfeld R, Liblau R, Wiendl H, Schwab N. Schneider-Hohendorf T, et al. Among authors: janoschka c. J Exp Med. 2022 Nov 7;219(11):e20220650. doi: 10.1084/jem.20220650. Epub 2022 Sep 1. J Exp Med. 2022. PMID: 36048016 Free PMC article.
B7-H1 shapes T-cell-mediated brain endothelial cell dysfunction and regional encephalitogenicity in spontaneous CNS autoimmunity.
Klotz L, Kuzmanov I, Hucke S, Gross CC, Posevitz V, Dreykluft A, Schulte-Mecklenbeck A, Janoschka C, Lindner M, Herold M, Schwab N, Ludwig-Portugall I, Kurts C, Meuth SG, Kuhlmann T, Wiendl H. Klotz L, et al. Among authors: janoschka c. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6182-E6191. doi: 10.1073/pnas.1601350113. Epub 2016 Sep 26. Proc Natl Acad Sci U S A. 2016. PMID: 27671636 Free PMC article.
Immune Cell Profiling During Switching from Natalizumab to Fingolimod Reveals Differential Effects on Systemic Immune-Regulatory Networks and on Trafficking of Non-T Cell Populations into the Cerebrospinal Fluid-Results from the ToFingo Successor Study.
Lohmann L, Janoschka C, Schulte-Mecklenbeck A, Klinsing S, Kirstein L, Hanning U, Wirth T, Schneider-Hohendorf T, Schwab N, Gross CC, Eveslage M, Meuth SG, Wiendl H, Klotz L. Lohmann L, et al. Among authors: janoschka c. Front Immunol. 2018 Jul 9;9:1560. doi: 10.3389/fimmu.2018.01560. eCollection 2018. Front Immunol. 2018. PMID: 30050529 Free PMC article.
Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.
Klotz L, Eschborn M, Lindner M, Liebmann M, Herold M, Janoschka C, Torres Garrido B, Schulte-Mecklenbeck A, Gross CC, Breuer J, Hundehege P, Posevitz V, Pignolet B, Nebel G, Glander S, Freise N, Austermann J, Wirth T, Campbell GR, Schneider-Hohendorf T, Eveslage M, Brassat D, Schwab N, Loser K, Roth J, Busch KB, Stoll M, Mahad DJ, Meuth SG, Turner T, Bar-Or A, Wiendl H. Klotz L, et al. Among authors: janoschka c. Sci Transl Med. 2019 May 1;11(490):eaao5563. doi: 10.1126/scitranslmed.aao5563. Sci Transl Med. 2019. PMID: 31043571 Clinical Trial.
Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis.
Herich S, Schneider-Hohendorf T, Rohlmann A, Khaleghi Ghadiri M, Schulte-Mecklenbeck A, Zondler L, Janoschka C, Ostkamp P, Richter J, Breuer J, Dimitrov S, Rammensee HG, Grauer OM, Klotz L, Gross CC, Stummer W, Missler M, Zarbock A, Vestweber D, Wiendl H, Schwab N. Herich S, et al. Among authors: janoschka c. Brain. 2019 Nov 1;142(11):3411-3427. doi: 10.1093/brain/awz301. Brain. 2019. PMID: 31563951
Immune signatures of prodromal multiple sclerosis in monozygotic twins.
Gerdes LA, Janoschka C, Eveslage M, Mannig B, Wirth T, Schulte-Mecklenbeck A, Lauks S, Glau L, Gross CC, Tolosa E, Flierl-Hecht A, Ertl-Wagner B, Barkhof F, Meuth SG, Kümpfel T, Wiendl H, Hohlfeld R, Klotz L. Gerdes LA, et al. Among authors: janoschka c. Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21546-21556. doi: 10.1073/pnas.2003339117. Epub 2020 Aug 17. Proc Natl Acad Sci U S A. 2020. PMID: 32817525 Free PMC article.
High anti-JCPyV serum titers coincide with high CSF cell counts in RRMS patients.
Schneider-Hohendorf T, Schulte-Mecklenbeck A, Ostkamp P, Janoschka C, Pawlitzki M, Luessi F, Zipp F, Meuth SG, Klotz L, Wiendl H, Gross CC, Schwab N. Schneider-Hohendorf T, et al. Among authors: janoschka c. Mult Scler. 2021 Sep;27(10):1491-1496. doi: 10.1177/1352458520970103. Epub 2020 Nov 5. Mult Scler. 2021. PMID: 33150829 Free PMC article.
Dietary conjugated linoleic acid links reduced intestinal inflammation to amelioration of CNS autoimmunity.
Fleck AK, Hucke S, Teipel F, Eschborn M, Janoschka C, Liebmann M, Wami H, Korn L, Pickert G, Hartwig M, Wirth T, Herold M, Koch K, Falk-Paulsen M, Dobrindt U, Kovac S, Gross CC, Rosenstiel P, Trautmann M, Wiendl H, Schuppan D, Kuhlmann T, Klotz L. Fleck AK, et al. Among authors: janoschka c. Brain. 2021 May 7;144(4):1152-1166. doi: 10.1093/brain/awab040. Brain. 2021. PMID: 33899089 Free PMC article. Clinical Trial.
Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity.
Liebmann M, Korn L, Janoschka C, Albrecht S, Lauks S, Herrmann AM, Schulte-Mecklenbeck A, Schwab N, Schneider-Hohendorf T, Eveslage M, Wildemann B, Luessi F, Schmidt S, Diebold M, Bittner S, Gross CC, Kovac S, Zipp F, Derfuss T, Kuhlmann T, König S, Meuth SG, Wiendl H, Klotz L. Liebmann M, et al. Among authors: janoschka c. Brain. 2021 Nov 29;144(10):3126-3141. doi: 10.1093/brain/awab307. Brain. 2021. PMID: 34849598 Free PMC article. Clinical Trial.
Correction: Broader Epstein-Barr virus-specific T cell receptor repertoire in patients with multiple sclerosis.
Schneider-Hohendorf T, Gerdes LA, Pignolet B, Gittelman R, Ostkamp P, Rubelt F, Raposo C, Tackenberg B, Riepenhausen M, Janoschka C, Wünsch C, Bucciarelli F, Flierl-Hecht A, Beltrán E, Kümpfel T, Anslinger K, Gross CC, Chapman H, Kaplan I, Brassat D, Wekerle H, Kerschensteiner M, Klotz L, Lünemann JD, Hohlfeld R, Liblau R, Wiendl H, Schwab N. Schneider-Hohendorf T, et al. Among authors: janoschka c. J Exp Med. 2022 Nov 7;219(11):e2022065010252022c. doi: 10.1084/jem.2022065010252022c. Epub 2022 Oct 28. J Exp Med. 2022. PMID: 36305889 Free PMC article. No abstract available.
14 results