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Novel cholinesterase modulators and their ability to interact with DNA.
Janockova J, Gulasova Z, Musilek K, Kuca K, Kozurkova M. Janockova J, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2013 Nov;115:364-9. doi: 10.1016/j.saa.2013.06.008. Epub 2013 Jun 17. Spectrochim Acta A Mol Biomol Spectrosc. 2013. PMID: 23851179
Synthesis and Biological Evaluation of Benzochromenopyrimidinones as Cholinesterase Inhibitors and Potent Antioxidant, Non-Hepatotoxic Agents for Alzheimer's Disease.
Dgachi Y, Bautista-Aguilera OM, Benchekroun M, Martin H, Bonet A, Knez D, Godyń J, Malawska B, Gobec S, Chioua M, Janockova J, Soukup O, Chabchoub F, Marco-Contelles J, Ismaili L. Dgachi Y, et al. Among authors: janockova j. Molecules. 2016 May 14;21(5):634. doi: 10.3390/molecules21050634. Molecules. 2016. PMID: 27187348 Free PMC article.
Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer's disease treatment.
Hroch L, Benek O, Guest P, Aitken L, Soukup O, Janockova J, Musil K, Dohnal V, Dolezal R, Kuca K, Smith TK, Gunn-Moore F, Musilek K. Hroch L, et al. Among authors: janockova j. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3675-8. doi: 10.1016/j.bmcl.2016.05.087. Epub 2016 May 30. Bioorg Med Chem Lett. 2016. PMID: 27287370
Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation.
Panek D, Więckowska A, Wichur T, Bajda M, Godyń J, Jończyk J, Mika K, Janockova J, Soukup O, Knez D, Korabecny J, Gobec S, Malawska B. Panek D, et al. Among authors: janockova j. Eur J Med Chem. 2017 Jan 5;125:676-695. doi: 10.1016/j.ejmech.2016.09.078. Epub 2016 Sep 26. Eur J Med Chem. 2017. PMID: 27721153
The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators.
Benchekroun M, Romero A, Egea J, León R, Michalska P, Buendía I, Jimeno ML, Jun D, Janockova J, Sepsova V, Soukup O, Bautista-Aguilera OM, Refouvelet B, Ouari O, Marco-Contelles J, Ismaili L. Benchekroun M, et al. Among authors: janockova j. J Med Chem. 2016 Nov 10;59(21):9967-9973. doi: 10.1021/acs.jmedchem.6b01178. Epub 2016 Oct 31. J Med Chem. 2016. PMID: 27736061
41 results