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A rapamycin-binding protein polymer nanoparticle shows potent therapeutic activity in suppressing autoimmune dacryoadenitis in a mouse model of Sjögren's syndrome.
Shah M, Edman MC, Janga SR, Shi P, Dhandhukia J, Liu S, Louie SG, Rodgers K, Mackay JA, Hamm-Alvarez SF. Shah M, et al. Among authors: janga sr. J Control Release. 2013 Nov 10;171(3):269-79. doi: 10.1016/j.jconrel.2013.07.016. Epub 2013 Jul 25. J Control Release. 2013. PMID: 23892265 Free PMC article.
Tear cathepsin S as a candidate biomarker for Sjögren's syndrome.
Hamm-Alvarez SF, Janga SR, Edman MC, Madrigal S, Shah M, Frousiakis SE, Renduchintala K, Zhu J, Bricel S, Silka K, Bach D, Heur M, Christianakis S, Arkfeld DG, Irvine J, Mack WJ, Stohl W. Hamm-Alvarez SF, et al. Among authors: janga sr. Arthritis Rheumatol. 2014 Jul;66(7):1872-81. doi: 10.1002/art.38633. Arthritis Rheumatol. 2014. PMID: 24644101 Free PMC article.
Increased Cathepsin S activity associated with decreased protease inhibitory capacity contributes to altered tear proteins in Sjögren's Syndrome patients.
Edman MC, Janga SR, Meng Z, Bechtold M, Chen AF, Kim C, Naman L, Sarma A, Teekappanavar N, Kim AY, Madrigal S, Singh S, Ortiz E, Christianakis S, Arkfeld DG, Mack WJ, Heur M, Stohl W, Hamm-Alvarez SF. Edman MC, et al. Among authors: janga sr. Sci Rep. 2018 Jul 23;8(1):11044. doi: 10.1038/s41598-018-29411-9. Sci Rep. 2018. PMID: 30038391 Free PMC article.
Intralacrimal Sustained Delivery of Rapamycin Shows Therapeutic Effects without Systemic Toxicity in a Mouse Model of Autoimmune Dacryoadenitis Characteristic of Sjögren's Syndrome.
Ju Y, Edman MC, Guo H, Janga SR, Peddi S, Louie SG, Junge JA, MacKay JA, Hamm-Alvarez SF. Ju Y, et al. Among authors: janga sr. Biomacromolecules. 2021 Mar 8;22(3):1102-1114. doi: 10.1021/acs.biomac.0c01468. Epub 2020 Dec 27. Biomacromolecules. 2021. PMID: 33356170 Free PMC article.
23 results