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A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fates.
He P, Lim K, Sun D, Pett JP, Jeng Q, Polanski K, Dong Z, Bolt L, Richardson L, Mamanova L, Dabrowska M, Wilbrey-Clark A, Madissoon E, Tuong ZK, Dann E, Suo C, Goh I, Yoshida M, Nikolić MZ, Janes SM, He X, Barker RA, Teichmann SA, Marioni JC, Meyer KB, Rawlins EL. He P, et al. Among authors: janes sm. Cell. 2022 Dec 8;185(25):4841-4860.e25. doi: 10.1016/j.cell.2022.11.005. Cell. 2022. PMID: 36493756 Free article.
Toll-like receptor 2 orchestrates a tumor suppressor response in non-small cell lung cancer.
Millar FR, Pennycuick A, Muir M, Quintanilla A, Hari P, Freyer E, Gautier P, Meynert A, Grimes G, Coll CS, Zdral S, Victorelli S, Teixeira VH, Connelly J, Passos JF, Ros MA, Wallace WAH, Frame MC, Sims AH, Boulter L, Janes SM, Wilkinson S, Acosta JC. Millar FR, et al. Among authors: janes sm. Cell Rep. 2022 Nov 8;41(6):111596. doi: 10.1016/j.celrep.2022.111596. Cell Rep. 2022. PMID: 36351380 Free PMC article.
Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer.
Pearce DR, Akarca AU, De Maeyer RPH, Kostina E, Huebner A, Sivakumar M, Karasaki T, Shah K, Janes SM, McGranahan N, Reddy V, Akbar AN, Moore DA, Marafioti T, Swanton C, Hynds RE. Pearce DR, et al. Among authors: janes sm. Front Oncol. 2023 Jun 5;13:1156743. doi: 10.3389/fonc.2023.1156743. eCollection 2023. Front Oncol. 2023. PMID: 37342197 Free PMC article.
Cell-intrinsic differences between human airway epithelial cells from children and adults.
Maughan EF, Hynds RE, Pennycuick A, Nigro E, Gowers KHC, Denais C, Gómez-López S, Lazarus KA, Orr JC, Pearce DR, Clarke SE, Lee DDH, Woodall MNJ, Masonou T, Case KM, Teixeira VH, Hartley BE, Hewitt RJ, Al Yaghchi C, Sandhu GS, Birchall MA, O'Callaghan C, Smith CM, De Coppi P, Butler CR, Janes SM. Maughan EF, et al. Among authors: janes sm. iScience. 2022 Oct 20;25(11):105409. doi: 10.1016/j.isci.2022.105409. eCollection 2022 Nov 18. iScience. 2022. PMID: 36388965 Free PMC article.
Lung viral infection modelling in a bioengineered whole-organ.
Tommasini F, Benoist T, Shibuya S, Woodall MNJ, Naldi E, Palor M, Orr JC, Giobbe GG, Maughan EF, Saleh T, Gjinovci A, Hutchinson JC, Arthurs OJ, Janes SM, Elvassore N, Hynds RE, Smith CM, Michielin F, Pellegata AF, De Coppi P. Tommasini F, et al. Among authors: janes sm. Biomaterials. 2023 Oct;301:122203. doi: 10.1016/j.biomaterials.2023.122203. Epub 2023 Jun 21. Biomaterials. 2023. PMID: 37515903 Free PMC article.
Stage at Diagnosis Following Delay to Interval Scans for Indeterminate Nodules in Lung Cancer Screening: An Observational Study Examining the Outcomes of CHEST Expert Panel Recommendations.
Creamer AW, Horst C, Dickson JL, Tisi S, Hall H, Verghese P, Prendecki R, Bhamani A, Khaw CR, McCabe J, Limani T, Gyertson K, Hacker AM, Teague J, Farrelly L, Dawadi S, Hackshaw A, Devaraj A, Nair A, Janes SM; SUMMIT Consortium. Creamer AW, et al. Among authors: janes sm. Chest. 2024 Apr;165(4):1020-1024. doi: 10.1016/j.chest.2023.10.033. Epub 2023 Oct 31. Chest. 2024. PMID: 37914027 Free PMC article. No abstract available.
Genetic screens reveal new targetable vulnerabilities in BAP1-deficient mesothelioma.
Pandey GK, Landman N, Neikes HK, Hulsman D, Lieftink C, Beijersbergen R, Kolluri KK, Janes SM, Vermeulen M, Badhai J, van Lohuizen M. Pandey GK, et al. Among authors: janes sm. Cell Rep Med. 2023 Feb 21;4(2):100915. doi: 10.1016/j.xcrm.2022.100915. Epub 2023 Jan 18. Cell Rep Med. 2023. PMID: 36657447 Free PMC article.
Prevalence and clinical characteristics of non-malignant CT detected incidental findings in the SUMMIT lung cancer screening cohort.
Tisi S, Creamer AW, Dickson J, Horst C, Quaife S, Hall H, Verghese P, Gyertson K, Bowyer V, Levermore C, Hacker AM, Teague J, Farrelly L, Nair A, Devaraj A, Hackshaw A, Hurst JR; SUMMIT Consortium; Janes S. Tisi S, et al. BMJ Open Respir Res. 2023 Jun;10(1):e001664. doi: 10.1136/bmjresp-2023-001664. BMJ Open Respir Res. 2023. PMID: 37321665 Free PMC article.
Genomic-transcriptomic evolution in lung cancer and metastasis.
Martínez-Ruiz C, Black JRM, Puttick C, Hill MS, Demeulemeester J, Larose Cadieux E, Thol K, Jones TP, Veeriah S, Naceur-Lombardelli C, Toncheva A, Prymas P, Rowan A, Ward S, Cubitt L, Athanasopoulou F, Pich O, Karasaki T, Moore DA, Salgado R, Colliver E, Castignani C, Dietzen M, Huebner A, Al Bakir M, Tanić M, Watkins TBK, Lim EL, Al-Rashed AM, Lang D, Clements J, Cook DE, Rosenthal R, Wilson GA, Frankell AM, de Carné Trécesson S, East P, Kanu N, Litchfield K, Birkbak NJ, Hackshaw A, Beck S, Van Loo P, Jamal-Hanjani M; TRACERx Consortium; Swanton C, McGranahan N. Martínez-Ruiz C, et al. Nature. 2023 Apr;616(7957):543-552. doi: 10.1038/s41586-023-05706-4. Epub 2023 Apr 12. Nature. 2023. PMID: 37046093 Free PMC article.
247 results