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Year Number of Results
2010 6
2011 3
2012 3
2013 4
2014 13
2015 8
2016 13
2017 14
2018 15
2019 23
2020 20
2021 25
2022 13
2023 11
2024 3

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148 results

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Page 1
Morphing cholinesterase inhibitor amiridine into multipotent drugs for the treatment of Alzheimer's disease.
Mezeiova E, Prchal L, Hrabinova M, Muckova L, Pulkrabkova L, Soukup O, Misiachna A, Janousek J, Fibigar J, Kucera T, Horak M, Makhaeva GF, Korabecny J. Mezeiova E, et al. Among authors: korabecny j. Biomed Pharmacother. 2024 Apr;173:116399. doi: 10.1016/j.biopha.2024.116399. Epub 2024 Mar 15. Biomed Pharmacother. 2024. PMID: 38492439 Free article.
Phenoxytacrine derivatives: Low-toxicity neuroprotectants exerting affinity to ifenprodil-binding site and cholinesterase inhibition.
Misiachna A, Svobodova B, Netolicky J, Chvojkova M, Kleteckova L, Prchal L, Novak M, Hrabinova M, Kucera T, Muckova L, Moravcova Z, Karasova JZ, Pejchal J, Blazek F, Malinak D, Hakenova K, Krausova BH, Kolcheva M, Ladislav M, Korabecny J, Pahnke J, Vales K, Horak M, Soukup O. Misiachna A, et al. Among authors: korabecny j. Eur J Med Chem. 2024 Feb 15;266:116130. doi: 10.1016/j.ejmech.2024.116130. Epub 2024 Jan 7. Eur J Med Chem. 2024. PMID: 38218127 Free article.
Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation.
Novak M, Vajrychova M, Koutsilieri S, Sismanoglou DC, Kobrlova T, Prchal L, Svobodova B, Korabecny J, Zarybnicky T, Raisova-Stuchlikova L, Skalova L, Lauschke VM, Kučera R, Soukup O. Novak M, et al. Among authors: korabecny j. ACS Chem Biol. 2023 Sep 15;18(9):1993-2002. doi: 10.1021/acschembio.3c00219. Epub 2023 Aug 25. ACS Chem Biol. 2023. PMID: 37622522
A-agents, misleadingly known as "Novichoks": a narrative review.
Opravil J, Pejchal J, Finger V, Korabecny J, Rozsypal T, Hrabinova M, Muckova L, Hepnarova V, Konecny J, Soukup O, Jun D. Opravil J, et al. Among authors: korabecny j. Arch Toxicol. 2023 Oct;97(10):2587-2607. doi: 10.1007/s00204-023-03571-8. Epub 2023 Aug 24. Arch Toxicol. 2023. PMID: 37612377 Free PMC article. Review.
2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1.
Finger V, Kucera T, Kafkova R, Muckova L, Dolezal R, Kubes J, Novak M, Prchal L, Lakatos L, Andrs M, Hympanova M, Marek J, Kufa M, Spiwok V, Soukup O, Mezeiova E, Janousek J, Nevosadova L, Benkova M, Kitson RRA, Kratky M, Bősze S, Mikusova K, Hartkoorn R, Roh J, Korabecny J. Finger V, et al. Among authors: korabecny j. Eur J Med Chem. 2023 Oct 5;258:115611. doi: 10.1016/j.ejmech.2023.115611. Epub 2023 Jul 3. Eur J Med Chem. 2023. PMID: 37421887 Free article.
Dopaminergic and glutamatergic models of psychosis show differential sensitivity to aripiprazole and a novel experimental compound modulating D2/5-HT receptor activity.
Vojtechova I, Tuckova K, Juza R, Stuchlik A, Kelemen E, Korabecny J, Soukup O, Petrasek T. Vojtechova I, et al. Among authors: korabecny j. Prog Neuropsychopharmacol Biol Psychiatry. 2023 Dec 20;127:110819. doi: 10.1016/j.pnpbp.2023.110819. Epub 2023 Jun 26. Prog Neuropsychopharmacol Biol Psychiatry. 2023. PMID: 37379895
Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.
Svobodova B, Pulkrabkova L, Panek D, Misiachna A, Kolcheva M, Andrys R, Handl J, Capek J, Nyvltova P, Rousar T, Prchal L, Hepnarova V, Hrabinova M, Muckova L, Tosnerova D, Karabanovich G, Finger V, Soukup O, Horak M, Korabecny J. Svobodova B, et al. Among authors: korabecny j. Int J Mol Sci. 2023 May 23;24(11):9124. doi: 10.3390/ijms24119124. Int J Mol Sci. 2023. PMID: 37298087 Free PMC article.
148 results