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Dementia risk reduction: why haven't the pharmacological risk reduction trials worked? An in-depth exploration of seven established risk factors.
Peters R, Breitner J, James S, Jicha GA, Meyer PF, Richards M, Smith AD, Yassine HN, Abner E, Hainsworth AH, Kehoe PG, Beckett N, Weber C, Anderson C, Anstey KJ, Dodge HH. Peters R, et al. Among authors: james s. Alzheimers Dement (N Y). 2021 Dec 8;7(1):e12202. doi: 10.1002/trc2.12202. eCollection 2021. Alzheimers Dement (N Y). 2021. PMID: 34934803 Free PMC article. Review.
The epidemiology is promising, but the trial evidence is weak. Why pharmacological dementia risk reduction trials haven't lived up to expectations, and where do we go from here?
Peters R, Dodge HH, James S, Jicha GA, Meyer PF, Richards M, Smith AD, Yassine HN, Abner E, Hainsworth AH, Kehoe PG, Beckett N, Anderson CS, Anstey KJ. Peters R, et al. Among authors: james s. Alzheimers Dement. 2022 Mar;18(3):507-512. doi: 10.1002/alz.12393. Epub 2021 Nov 2. Alzheimers Dement. 2022. PMID: 34726352
Pure tone audiometry and cerebral pathology in healthy older adults.
Parker T, Cash DM, Lane C, Lu K, Malone IB, Nicholas JM, James S, Keshavan A, Murray-Smith H, Wong A, Buchannan S, Keuss S, Sudre CH, Thomas D, Crutch S, Bamiou DE, Warren JD, Fox NC, Richards M, Schott JM. Parker T, et al. Among authors: james s. J Neurol Neurosurg Psychiatry. 2020 Feb;91(2):172-176. doi: 10.1136/jnnp-2019-321897. Epub 2019 Nov 7. J Neurol Neurosurg Psychiatry. 2020. PMID: 31699832 Free PMC article.
A pilot study of the contribution of energy-dense Caribbean diets to acrylamide exposure with associated health risks for a population of university students in Trinidad and Tobago.
Augustine DA, Dookeram N, Albert S, James S, Bent GA. Augustine DA, et al. Among authors: james s. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2024 May 9:1-14. doi: 10.1080/19440049.2024.2351986. Online ahead of print. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2024. PMID: 38723154
The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months.
Carey ME, Kivumbi A, Rando J, Mesaros AC, Melnyk S, James SJ, Croen LA, Volk H, Lyall K; Early Autism Risk Longitudinal Investigation (EARLI) team. Carey ME, et al. Among authors: james sj. Brain Behav Immun Health. 2024 Apr 24;38:100775. doi: 10.1016/j.bbih.2024.100775. eCollection 2024 Jul. Brain Behav Immun Health. 2024. PMID: 38706573 Free PMC article.
Liver regeneration after portal and hepatic vein embolization improves overall survival compared with portal vein embolization alone: mid-term survival analysis of the multicentre DRAGON 0 cohort.
Korenblik R, Heil J, Smits J, James S, Olij B, Bechstein WO, Bemelmans MHA, Binkert CA, Breitenstein S, Williams M, Detry O, Dewulf MJL, Dili A, Grochola LF, Grote J, Heise D, Kalil JA, Metrakos P, Neumann UP, Pappas SG, Pennetta F, Schnitzbauer AA, Tasse JC, Winkens B, Olde Damink SWM, van der Leij C, Schadde E, van Dam RM; DRAGON trials collaborative. Korenblik R, et al. Among authors: james s. Br J Surg. 2024 Apr 3;111(4):znae087. doi: 10.1093/bjs/znae087. Br J Surg. 2024. PMID: 38662462 Free PMC article.
Phylogenomics and the rise of the angiosperms.
Zuntini AR, Carruthers T, Maurin O, Bailey PC, Leempoel K, Brewer GE, Epitawalage N, Françoso E, Gallego-Paramo B, McGinnie C, Negrão R, Roy SR, Simpson L, Toledo Romero E, Barber VMA, Botigué L, Clarkson JJ, Cowan RS, Dodsworth S, Johnson MG, Kim JT, Pokorny L, Wickett NJ, Antar GM, DeBolt L, Gutierrez K, Hendriks KP, Hoewener A, Hu AQ, Joyce EM, Kikuchi IABS, Larridon I, Larson DA, de Lírio EJ, Liu JX, Malakasi P, Przelomska NAS, Shah T, Viruel J, Allnutt TR, Ameka GK, Andrew RL, Appelhans MS, Arista M, Ariza MJ, Arroyo J, Arthan W, Bachelier JB, Bailey CD, Barnes HF, Barrett MD, Barrett RL, Bayer RJ, Bayly MJ, Biffin E, Biggs N, Birch JL, Bogarín D, Borosova R, Bowles AMC, Boyce PC, Bramley GLC, Briggs M, Broadhurst L, Brown GK, Bruhl JJ, Bruneau A, Buerki S, Burns E, Byrne M, Cable S, Calladine A, Callmander MW, Cano Á, Cantrill DJ, Cardinal-McTeague WM, Carlsen MM, Carruthers AJA, de Castro Mateo A, Chase MW, Chatrou LW, Cheek M, Chen S, Christenhusz MJM, Christin PA, Clements MA, Coffey SC, Conran JG, Cornejo X, Couvreur TLP, Cowie ID, Csiba L, Darbyshire I, Davidse G, Davies NMJ, Davis AP, van Dijk KJ, Downie SR, Duretto MF, Duvall MR, Edwards SL, Eggli U, Erkens RHJ, Escud… See abstract for full author list ➔ Zuntini AR, et al. Among authors: james sa. Nature. 2024 Apr 24. doi: 10.1038/s41586-024-07324-0. Online ahead of print. Nature. 2024. PMID: 38658746
3,502 results