Jakopin Ž - Search Results

1

Benzimidazole-galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimisation.

Hassan M, van Klaveren S, Håkansson M, Diehl C, Kovačič R, Baussière F, Sundin AP, Dernovšek J, Walse B, Zetterberg F, Leffler H, Anderluh M, Tomašič T, Jakopin Ž, Nilsson UJ. Hassan M, et al. Among authors: jakopin z. Eur J Med Chem. 2021 Nov 5;223:113664. doi: 10.1016/j.ejmech.2021.113664. Epub 2021 Jun 25. Eur J Med Chem. 2021. PMID: 34225180 Free article.

2

3,4-Dihydro-2H-1,4-benzoxazine derivatives combining thrombin inhibitory and glycoprotein IIb/IIIa receptor antagonistic activity as a novel class of antithrombotic compounds with dual function.

Ilas J, Jakopin Z, Borstnar T, Stegnar M, Kikelj D. Ilas J, et al. Among authors: jakopin z. J Med Chem. 2008 Sep 25;51(18):5617-29. doi: 10.1021/jm8003448. Epub 2008 Aug 27. J Med Chem. 2008. PMID: 18729445

3

Design, synthesis and biological evaluation of novel desmuramyldipeptide analogs.

Jakopin Ž, Corsini E, Gobec M, Mlinarič-Raščan I, Dolenc MS. Jakopin Ž, et al. Eur J Med Chem. 2011 Sep;46(9):3762-77. doi: 10.1016/j.ejmech.2011.05.042. Epub 2011 May 27. Eur J Med Chem. 2011. PMID: 21669478

4

Synthesis of conformationally constrained γ-D-glutamyl-meso-diaminopimelic acid derivatives as ligands of nucleotide-binding oligomerization domain protein 1 (Nod1).

Jakopin Ž, Gobec M, Kodela J, Hazdovac T, Mlinarič-Raščan I, Sollner Dolenc M. Jakopin Ž, et al. Eur J Med Chem. 2013 Nov;69:232-43. doi: 10.1016/j.ejmech.2013.08.022. Epub 2013 Aug 30. Eur J Med Chem. 2013. PMID: 24044936

5

Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4,5-dihydro-2-aminoimidazoles as voltage-gated sodium channel modulators.

Zidar N, Jakopin Ž, Madge DJ, Chan F, Tytgat J, Peigneur S, Dolenc MS, Tomašić T, Ilaš J, Mašič LP, Kikelj D. Zidar N, et al. Among authors: jakopin z. Eur J Med Chem. 2014 Mar 3;74:23-30. doi: 10.1016/j.ejmech.2013.12.034. Epub 2014 Jan 3. Eur J Med Chem. 2014. PMID: 24440379

6

Nucleotide-binding oligomerization domain (NOD) inhibitors: a rational approach toward inhibition of NOD signaling pathway.

Jakopin Ž. Jakopin Ž. J Med Chem. 2014 Aug 28;57(16):6897-918. doi: 10.1021/jm401841p. Epub 2014 Apr 22. J Med Chem. 2014. PMID: 24707857 Review.

7

Antioxidant and anti-inflammatory properties of 1,2,4-oxadiazole analogs of resveratrol.

Gobec M, Tomašič T, Markovič T, Mlinarič-Raščan I, Dolenc MS, Jakopin Ž. Gobec M, et al. Among authors: jakopin z. Chem Biol Interact. 2015 Oct 5;240:200-7. doi: 10.1016/j.cbi.2015.08.018. Epub 2015 Aug 31. Chem Biol Interact. 2015. PMID: 26335192

8

Structural requirements of acylated Gly-l-Ala-d-Glu analogs for activation of the innate immune receptor NOD2.

Gobec M, Mlinarič-Raščan I, Dolenc MS, Jakopin Ž. Gobec M, et al. Among authors: jakopin z. Eur J Med Chem. 2016 Jun 30;116:1-12. doi: 10.1016/j.ejmech.2016.03.030. Epub 2016 Mar 16. Eur J Med Chem. 2016. PMID: 27039337

9

Identification of indole scaffold-based dual inhibitors of NOD1 and NOD2.

Keček Plešec K, Urbančič D, Gobec M, Pekošak A, Tomašič T, Anderluh M, Mlinarič-Raščan I, Jakopin Ž. Keček Plešec K, et al. Among authors: jakopin z. Bioorg Med Chem. 2016 Nov 1;24(21):5221-5234. doi: 10.1016/j.bmc.2016.08.044. Epub 2016 Aug 24. Bioorg Med Chem. 2016. PMID: 27601373

10

Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors.

Jakopin Ž, Ilaš J, Barančoková M, Brvar M, Tammela P, Sollner Dolenc M, Tomašič T, Kikelj D. Jakopin Ž, et al. Eur J Med Chem. 2017 Apr 21;130:171-184. doi: 10.1016/j.ejmech.2017.02.046. Epub 2017 Feb 22. Eur J Med Chem. 2017. PMID: 28246042

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