Jaki T - Search Results

1

A surface-free design for phase I dual-agent combination trials.

Mozgunov P, Gasparini M, Jaki T. Mozgunov P, et al. Among authors: jaki t. Stat Methods Med Res. 2020 Oct;29(10):3093-3109. doi: 10.1177/0962280220919450. Epub 2020 Apr 27. Stat Methods Med Res. 2020. PMID: 32338145 Free PMC article.

2

One- and two-stage design proposals for a phase II trial comparing three active treatments with control using an ordered categorical endpoint.

Whitehead J, Jaki T. Whitehead J, et al. Among authors: jaki t. Stat Med. 2009 Feb 28;28(5):828-47. doi: 10.1002/sim.3508. Stat Med. 2009. PMID: 19061203

3

A novel Phase I/IIa design for early phase oncology studies and its application in the evaluation of MK-0752 in pancreatic cancer.

Whitehead J, Thygesen H, Jaki T, Davies S, Halford S, Turner H, Cook N, Jodrell D. Whitehead J, et al. Among authors: jaki t. Stat Med. 2012 Aug 15;31(18):1931-43. doi: 10.1002/sim.5331. Epub 2012 Apr 11. Stat Med. 2012. PMID: 22495759

4

Some recommendations for multi-arm multi-stage trials.

Wason J, Magirr D, Law M, Jaki T. Wason J, et al. Among authors: jaki t. Stat Methods Med Res. 2016 Apr;25(2):716-27. doi: 10.1177/0962280212465498. Epub 2012 Dec 12. Stat Methods Med Res. 2016. PMID: 23242385 Free PMC article.

5

Principles of dose finding studies in cancer: a comparison of trial designs.

Jaki T, Clive S, Weir CJ. Jaki T, et al. Cancer Chemother Pharmacol. 2013 May;71(5):1107-14. doi: 10.1007/s00280-012-2059-8. Epub 2013 Jan 9. Cancer Chemother Pharmacol. 2013. PMID: 23299793 Free PMC article. Review.

6

A practical design for a dual-agent dose-escalation trial that incorporates pharmacokinetic data.

Cotterill A, Lorand D, Wang J, Jaki T. Cotterill A, et al. Among authors: jaki t. Stat Med. 2015 Jun 15;34(13):2138-64. doi: 10.1002/sim.6482. Epub 2015 Mar 24. Stat Med. 2015. PMID: 25809576

7

A review of statistical designs for improving the efficiency of phase II studies in oncology.

Wason JM, Jaki T. Wason JM, et al. Among authors: jaki t. Stat Methods Med Res. 2016 Jun;25(3):1010-21. doi: 10.1177/0962280215588247. Epub 2015 May 31. Stat Methods Med Res. 2016. PMID: 26031358 Review.

8

Identification of predicted individual treatment effects in randomized clinical trials.

Lamont A, Lyons MD, Jaki T, Stuart E, Feaster DJ, Tharmaratnam K, Oberski D, Ishwaran H, Wilson DK, Van Horn ML. Lamont A, et al. Among authors: jaki t. Stat Methods Med Res. 2018 Jan;27(1):142-157. doi: 10.1177/0962280215623981. Epub 2016 Mar 17. Stat Methods Med Res. 2018. PMID: 26988928

9

Extrapolation of efficacy and other data to support the development of new medicines for children: A systematic review of methods.

Wadsworth I, Hampson LV, Jaki T. Wadsworth I, et al. Among authors: jaki t. Stat Methods Med Res. 2018 Feb;27(2):398-413. doi: 10.1177/0962280216631359. Epub 2016 Mar 17. Stat Methods Med Res. 2018. PMID: 26994211

10

A framework for prospectively defining progression rules for internal pilot studies monitoring recruitment.

Hampson LV, Williamson PR, Wilby MJ, Jaki T. Hampson LV, et al. Among authors: jaki t. Stat Methods Med Res. 2018 Dec;27(12):3612-3627. doi: 10.1177/0962280217708906. Epub 2017 Jun 7. Stat Methods Med Res. 2018. PMID: 28589752

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