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High-throughput Oligopaint screen identifies druggable 3D genome regulators.
Park DS, Nguyen SC, Isenhart R, Shah PP, Kim W, Barnett RJ, Chandra A, Luppino JM, Harke J, Wai M, Walsh PJ, Abdill RJ, Yang R, Lan Y, Yoon S, Yunker R, Kanemaki MT, Vahedi G, Phillips-Cremins JE, Jain R, Joyce EF. Park DS, et al. Among authors: jain r. Nature. 2023 Aug;620(7972):209-217. doi: 10.1038/s41586-023-06340-w. Epub 2023 Jul 12. Nature. 2023. PMID: 37438531
Genome-Nuclear Lamina Interactions Regulate Cardiac Stem Cell Lineage Restriction.
Poleshko A, Shah PP, Gupta M, Babu A, Morley MP, Manderfield LJ, Ifkovits JL, Calderon D, Aghajanian H, Sierra-Pagán JE, Sun Z, Wang Q, Li L, Dubois NC, Morrisey EE, Lazar MA, Smith CL, Epstein JA, Jain R. Poleshko A, et al. Among authors: jain r. Cell. 2017 Oct 19;171(3):573-587.e14. doi: 10.1016/j.cell.2017.09.018. Epub 2017 Oct 12. Cell. 2017. PMID: 29033129 Free PMC article.
BRD4 (Bromodomain-Containing Protein 4) Interacts with GATA4 (GATA Binding Protein 4) to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes.
Padmanabhan A, Alexanian M, Linares-Saldana R, González-Terán B, Andreoletti G, Huang Y, Connolly AJ, Kim W, Hsu A, Duan Q, Winchester SAB, Felix F, Perez-Bermejo JA, Wang Q, Li L, Shah PP, Haldar SM, Jain R, Srivastava D. Padmanabhan A, et al. Among authors: jain r. Circulation. 2020 Dec 15;142(24):2338-2355. doi: 10.1161/CIRCULATIONAHA.120.047753. Epub 2020 Oct 23. Circulation. 2020. PMID: 33094644 Free PMC article.
5,303 results