Jain AK - Search Results

1

Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8⁺ T cells.

Mahadevan KK, LeBleu VS, Ramirez EV, Chen Y, Li B, Sockwell AM, Gagea M, Sugimoto H, Sthanam LK, Tampe D, Zeisberg M, Ying H, Jain AK, DePinho RA, Maitra A, McAndrews KM, Kalluri R. Mahadevan KK, et al. Among authors: jain ak. Dev Cell. 2023 Sep 11;58(17):1562-1577.e8. doi: 10.1016/j.devcel.2023.07.025. Epub 2023 Aug 24. Dev Cell. 2023. PMID: 37625403

2

Aberrant expression of embryonic mesendoderm factor MESP1 promotes tumorigenesis.

Tandon N, Goller K, Wang F, Soibam B, Gagea M, Jain AK, Schwartz RJ, Liu Y. Tandon N, et al. Among authors: jain ak. EBioMedicine. 2019 Dec;50:55-66. doi: 10.1016/j.ebiom.2019.11.012. Epub 2019 Nov 21. EBioMedicine. 2019. PMID: 31761621 Free PMC article.

3

Mammary-specific expression of Trim24 establishes a mouse model of human metaplastic breast cancer.

Shah VV, Duncan AD, Jiang S, Stratton SA, Allton KL, Yam C, Jain A, Krause PM, Lu Y, Cai S, Tu Y, Zhou X, Zhang X, Jiang Y, Carroll CL, Kang Z, Liu B, Shen J, Gagea M, Manu SM, Huo L, Gilcrease M, Powell RT, Guo L, Stephan C, Davies PJ, Parker-Thornburg J, Lozano G, Behringer RR, Piwnica-Worms H, Chang JT, Moulder SL, Barton MC. Shah VV, et al. Nat Commun. 2021 Sep 10;12(1):5389. doi: 10.1038/s41467-021-25650-z. Nat Commun. 2021. PMID: 34508101 Free PMC article.

4

Outside the p53 RING: Transcription Regulation by Chromatin-Bound MDM2.

Jain AK, Barton MC. Jain AK, et al. Mol Cell. 2016 Jun 16;62(6):805-807. doi: 10.1016/j.molcel.2016.05.035. Mol Cell. 2016. PMID: 27315554 Free article.

5

LncPRESS1 Is a p53-Regulated LncRNA that Safeguards Pluripotency by Disrupting SIRT6-Mediated De-acetylation of Histone H3K56.

Jain AK, Xi Y, McCarthy R, Allton K, Akdemir KC, Patel LR, Aronow B, Lin C, Li W, Yang L, Barton MC. Jain AK, et al. Mol Cell. 2016 Dec 1;64(5):967-981. doi: 10.1016/j.molcel.2016.10.039. Mol Cell. 2016. PMID: 27912097 Free PMC article.

6

TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.

Li J, Xi Y, Li W, McCarthy RL, Stratton SA, Zou W, Li W, Dent SY, Jain AK, Barton MC. Li J, et al. Among authors: jain ak. Oncogene. 2017 May 25;36(21):2991-3001. doi: 10.1038/onc.2016.453. Epub 2017 Jan 9. Oncogene. 2017. PMID: 28068325 Free PMC article.

7

p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells.

Jain AK, Allton K, Iacovino M, Mahen E, Milczarek RJ, Zwaka TP, Kyba M, Barton MC. Jain AK, et al. PLoS Biol. 2012;10(2):e1001268. doi: 10.1371/journal.pbio.1001268. Epub 2012 Feb 28. PLoS Biol. 2012. PMID: 22389628 Free PMC article.

8

Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program.

Gencel-Augusto J, Su X, Qi Y, Whitley EM, Pant V, Xiong S, Shah V, Lin J, Perez E, Fiorotto ML, Mahmud I, Jain AK, Lorenzi PL, Navin NE, Richie ER, Lozano G. Gencel-Augusto J, et al. Among authors: jain ak. Cancer Discov. 2023 May 4;13(5):1230-1249. doi: 10.1158/2159-8290.CD-22-0872. Cancer Discov. 2023. PMID: 37067911 Free PMC article.

9

Histone demethylase KDM5 regulates cardiomyocyte maturation by promoting fatty acid oxidation, oxidative phosphorylation, and myofibrillar organization.

Deogharia M, Venegas-Zamora L, Agrawal A, Shi M, Jain AK, McHugh KJ, Altamirano F, Marian AJ, Gurha P. Deogharia M, et al. Among authors: jain ak. Cardiovasc Res. 2024 May 7;120(6):630-643. doi: 10.1093/cvr/cvae014. Cardiovasc Res. 2024. PMID: 38230606

10

Regulation of p53: TRIM24 enters the RING.

Jain AK, Barton MC. Jain AK, et al. Cell Cycle. 2009 Nov 15;8(22):3668-74. doi: 10.4161/cc.8.22.9979. Epub 2009 Nov 2. Cell Cycle. 2009. PMID: 19844164 Review.

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