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The thioredoxin-like protein rod-derived cone viability factor (RdCVFL) interacts with TAU and inhibits its phosphorylation in the retina.
Fridlich R, Delalande F, Jaillard C, Lu J, Poidevin L, Cronin T, Perrocheau L, Millet-Puel G, Niepon ML, Poch O, Holmgren A, Van Dorsselaer A, Sahel JA, Léveillard T. Fridlich R, et al. Among authors: jaillard c. Mol Cell Proteomics. 2009 Jun;8(6):1206-18. doi: 10.1074/mcp.M800406-MCP200. Epub 2009 Mar 11. Mol Cell Proteomics. 2009. PMID: 19279044 Free PMC article.
The disruption of the rod-derived cone viability gene leads to photoreceptor dysfunction and susceptibility to oxidative stress.
Cronin T, Raffelsberger W, Lee-Rivera I, Jaillard C, Niepon ML, Kinzel B, Clérin E, Petrosian A, Picaud S, Poch O, Sahel JA, Léveillard T. Cronin T, et al. Among authors: jaillard c. Cell Death Differ. 2010 Jul;17(7):1199-210. doi: 10.1038/cdd.2010.2. Epub 2010 Feb 5. Cell Death Differ. 2010. PMID: 20139892 Free PMC article.
Nxnl2 splicing results in dual functions in neuronal cell survival and maintenance of cell integrity.
Jaillard C, Mouret A, Niepon ML, Clérin E, Yang Y, Lee-Rivera I, Aït-Ali N, Millet-Puel G, Cronin T, Sedmak T, Raffelsberger W, Kinzel B, Trembleau A, Poch O, Bennett J, Wolfrum U, Lledo PM, Sahel JA, Léveillard T. Jaillard C, et al. Hum Mol Genet. 2012 May 15;21(10):2298-311. doi: 10.1093/hmg/dds050. Epub 2012 Feb 15. Hum Mol Genet. 2012. PMID: 22343139 Free PMC article.
Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis.
Aït-Ali N, Fridlich R, Millet-Puel G, Clérin E, Delalande F, Jaillard C, Blond F, Perrocheau L, Reichman S, Byrne LC, Olivier-Bandini A, Bellalou J, Moyse E, Bouillaud F, Nicol X, Dalkara D, van Dorsselaer A, Sahel JA, Léveillard T. Aït-Ali N, et al. Among authors: jaillard c. Cell. 2015 May 7;161(4):817-32. doi: 10.1016/j.cell.2015.03.023. Cell. 2015. PMID: 25957687 Free article.
A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina.
Chaffiol A, Caplette R, Jaillard C, Brazhnikova E, Desrosiers M, Dubus E, Duhamel L, Macé E, Marre O, Benoit P, Hantraye P, Bemelmans AP, Bamberg E, Duebel J, Sahel JA, Picaud S, Dalkara D. Chaffiol A, et al. Among authors: jaillard c. Mol Ther. 2017 Nov 1;25(11):2546-2560. doi: 10.1016/j.ymthe.2017.07.011. Epub 2017 Jul 20. Mol Ther. 2017. PMID: 28807567 Free PMC article.
Noninvasive gene delivery to foveal cones for vision restoration.
Khabou H, Garita-Hernandez M, Chaffiol A, Reichman S, Jaillard C, Brazhnikova E, Bertin S, Forster V, Desrosiers M, Winckler C, Goureau O, Picaud S, Duebel J, Sahel JA, Dalkara D. Khabou H, et al. Among authors: jaillard c. JCI Insight. 2018 Jan 25;3(2):e96029. doi: 10.1172/jci.insight.96029. eCollection 2018 Jan 25. JCI Insight. 2018. PMID: 29367457 Free PMC article.
Clinical-grade production and safe delivery of human ESC derived RPE sheets in primates and rodents.
Ben M'Barek K, Bertin S, Brazhnikova E, Jaillard C, Habeler W, Plancheron A, Fovet CM, Demilly J, Jarraya M, Bejanariu A, Sahel JA, Peschanski M, Goureau O, Monville C. Ben M'Barek K, et al. Among authors: jaillard c. Biomaterials. 2020 Feb;230:119603. doi: 10.1016/j.biomaterials.2019.119603. Epub 2019 Nov 6. Biomaterials. 2020. PMID: 31732225 Free article.
AAV-Mediated Gene Delivery to Foveal Cones.
Bertin S, Brazhnikova E, Jaillard C, Sahel JA, Dalkara D. Bertin S, et al. Among authors: jaillard c. Methods Mol Biol. 2020;2173:101-112. doi: 10.1007/978-1-0716-0755-8_6. Methods Mol Biol. 2020. PMID: 32651912
56 results