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Inhibition of LILRB2 by a Novel Blocking Antibody Designed to Reprogram Immunosuppressive Macrophages to Drive T-Cell Activation in Tumors.
Umiker B, Hashambhoy-Ramsay Y, Smith J, Rahman T, Mueller A, Davidson R, Meyer C, Patankar G, Alam MM, Jaffe S, Krukenberg K, Goodman A, Spaulding V, Priess M, Dhaneshwar A, Wong M, Diiorio A, O'Malley K, McGrath L, Willer M, Pepper L, Gostissa M, Kis-Toth K, Wiederschain D, Cohen H, Shaffer DR. Umiker B, et al. Among authors: jaffe s. Mol Cancer Ther. 2023 Apr 3;22(4):471-484. doi: 10.1158/1535-7163.MCT-22-0351. Mol Cancer Ther. 2023. PMID: 36780212
Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody.
Weaver JD, Stack EC, Buggé JA, Hu C, McGrath L, Mueller A, Wong M, Klebanov B, Rahman T, Kaufman R, Fregeau C, Spaulding V, Priess M, Legendre K, Jaffe S, Upadhyay D, Singh A, Xu CA, Krukenberg K, Zhang Y, Ezzyat Y, Saddier Axe D, Kuhne MR, Meehl MA, Shaffer DR, Weist BM, Wiederschain D, Depis F, Gostissa M. Weaver JD, et al. Among authors: jaffe s. Oncoimmunology. 2022 Nov 4;11(1):2141007. doi: 10.1080/2162402X.2022.2141007. eCollection 2022. Oncoimmunology. 2022. PMID: 36352891 Free PMC article.
Navigating the new normal: Examining coattendance in a hybrid work environment.
Charpignon ML, Yuan Y, Zhang D, Amini F, Yang L, Jaffe S, Suri S. Charpignon ML, et al. Among authors: jaffe s. Proc Natl Acad Sci U S A. 2023 Dec 19;120(51):e2310431120. doi: 10.1073/pnas.2310431120. Epub 2023 Dec 11. Proc Natl Acad Sci U S A. 2023. PMID: 38079553 Free PMC article.
273 results