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Angiotensin-Converting Enzyme 2 (ACE2), Transmembrane Peptidase Serine 2 (TMPRSS2), and Furin Expression Increases in the Lungs of Patients with Idiopathic Pulmonary Fibrosis (IPF) and Lymphangioleiomyomatosis (LAM): Implications for SARS-CoV-2 (COVID-19) Infections.
Lu W, Eapen MS, Singhera GK, Markos J, Haug G, Chia C, Larby J, Brake SJ, Westall GP, Jaffar J, Kalidhindi RSR, Fonseka N, Sathish V, Hackett TL, Sohal SS. Lu W, et al. Among authors: jaffar j. J Clin Med. 2022 Jan 31;11(3):777. doi: 10.3390/jcm11030777. J Clin Med. 2022. PMID: 35160229 Free PMC article.
Annexin A2 contributes to lung injury and fibrosis by augmenting factor Xa fibrogenic activity.
Schuliga M, Jaffar J, Berhan A, Langenbach S, Harris T, Waters D, Lee PVS, Grainge C, Westall G, Knight D, Stewart AG. Schuliga M, et al. Among authors: jaffar j. Am J Physiol Lung Cell Mol Physiol. 2017 May 1;312(5):L772-L782. doi: 10.1152/ajplung.00553.2016. Epub 2017 Mar 10. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28283478 Free article.
Casein Kinase 1δ/ε Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor-β in Pulmonary Fibrosis.
Keenan CR, Langenbach SY, Jativa F, Harris T, Li M, Chen Q, Xia Y, Gao B, Schuliga MJ, Jaffar J, Prodanovic D, Tu Y, Berhan A, Lee PVS, Westall GP, Stewart AG. Keenan CR, et al. Among authors: jaffar j. Front Pharmacol. 2018 Jul 10;9:738. doi: 10.3389/fphar.2018.00738. eCollection 2018. Front Pharmacol. 2018. PMID: 30042678 Free PMC article.
Mitochondrial dysfunction contributes to the senescent phenotype of IPF lung fibroblasts.
Schuliga M, Pechkovsky DV, Read J, Waters DW, Blokland KEC, Reid AT, Hogaboam CM, Khalil N, Burgess JK, Prêle CM, Mutsaers SE, Jaffar J, Westall G, Grainge C, Knight DA. Schuliga M, et al. Among authors: jaffar j. J Cell Mol Med. 2018 Dec;22(12):5847-5861. doi: 10.1111/jcmm.13855. Epub 2018 Sep 26. J Cell Mol Med. 2018. PMID: 30255990 Free PMC article.
STAT3 Regulates the Onset of Oxidant-induced Senescence in Lung Fibroblasts.
Waters DW, Blokland KEC, Pathinayake PS, Wei L, Schuliga M, Jaffar J, Westall GP, Hansbro PM, Prele CM, Mutsaers SE, Bartlett NW, Burgess JK, Grainge CL, Knight DA. Waters DW, et al. Among authors: jaffar j. Am J Respir Cell Mol Biol. 2019 Jul;61(1):61-73. doi: 10.1165/rcmb.2018-0328OC. Am J Respir Cell Mol Biol. 2019. PMID: 30608861
42 results