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How paediatric drug development and use could benefit from OMICs: A c4c expert group white paper.
Neumann E, Schreeck F, Herberg J, Jacqz Aigrain E, Maitland-van der Zee AH, Pérez-Martínez A, Hawcutt DB, Schaeffeler E, Rane A, de Wildt SN, Schwab M. Neumann E, et al. Among authors: jacqz aigrain e. Br J Clin Pharmacol. 2022 Dec;88(12):5017-5033. doi: 10.1111/bcp.15216. Epub 2022 Feb 9. Br J Clin Pharmacol. 2022. PMID: 34997627 Free article. Review.
Integration of pharmacogenetics and pharmacogenomics in drug development: implications for regulatory and medical decision making in pediatric diseases.
Piana C, Surh L, Furst-Recktenwald S, Iolascon A, Jacqz-Aigrain EM, Jonker I, Russo R, van Schaik RH, Wessels J, Della Pasqua OE. Piana C, et al. Among authors: jacqz aigrain em. J Clin Pharmacol. 2012 May;52(5):704-16. doi: 10.1177/0091270011401619. Epub 2011 May 12. J Clin Pharmacol. 2012. PMID: 21566202 Review.
Dose evaluation of lamivudine in human immunodeficiency virus-infected children aged 5 months to 18 years based on a population pharmacokinetic analysis.
Janssen EJH, Bastiaans DET, Välitalo PAJ, van Rossum AMC, Jacqz-Aigrain E, Lyall H, Knibbe CAJ, Burger DM. Janssen EJH, et al. Among authors: jacqz aigrain e. Br J Clin Pharmacol. 2017 Jun;83(6):1287-1297. doi: 10.1111/bcp.13227. Epub 2017 Feb 14. Br J Clin Pharmacol. 2017. PMID: 28079918 Free PMC article. Clinical Trial.
Predicting CYP3A-mediated midazolam metabolism in critically ill neonates, infants, children and adults with inflammation and organ failure.
Brussee JM, Vet NJ, Krekels EHJ, Valkenburg AJ, Jacqz-Aigrain E, van Gerven JMA, Swart EL, van den Anker JN, Tibboel D, de Hoog M, de Wildt SN, Knibbe CAJ. Brussee JM, et al. Among authors: jacqz aigrain e. Br J Clin Pharmacol. 2018 Feb;84(2):358-368. doi: 10.1111/bcp.13459. Epub 2017 Nov 29. Br J Clin Pharmacol. 2018. PMID: 29072785 Free PMC article.
Pharmacokinetics and safety of fluconazole and micafungin in neonates with systemic candidiasis: a randomized, open-label clinical trial.
Leroux S, Jacqz-Aigrain E, Elie V, Legrand F, Barin-Le Guellec C, Aurich B, Biran V, Dusang B, Goudjil S, Coopman S, Garcia Sanchez R, Zhao W, Manzoni P; FP7 TINN (Treat Infections in NeoNates) consortium. Leroux S, et al. Among authors: jacqz aigrain e. Br J Clin Pharmacol. 2018 Sep;84(9):1989-1999. doi: 10.1111/bcp.13628. Epub 2018 Jun 21. Br J Clin Pharmacol. 2018. PMID: 29744900 Free PMC article. Clinical Trial.
329 results