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Deubiquitylating enzymes and drug discovery: emerging opportunities.
Harrigan JA, Jacq X, Martin NM, Jackson SP. Harrigan JA, et al. Among authors: jacq x. Nat Rev Drug Discov. 2018 Jan;17(1):57-78. doi: 10.1038/nrd.2017.152. Epub 2017 Sep 29. Nat Rev Drug Discov. 2018. PMID: 28959952 Free PMC article. Review.
Deubiquitylating enzymes and DNA damage response pathways.
Jacq X, Kemp M, Martin NM, Jackson SP. Jacq X, et al. Cell Biochem Biophys. 2013 Sep;67(1):25-43. doi: 10.1007/s12013-013-9635-3. Cell Biochem Biophys. 2013. PMID: 23712866 Free PMC article. Review.
A population-based analysis of germline BAP1 mutations in melanoma.
O'Shea SJ, Robles-Espinoza CD, McLellan L, Harrigan J, Jacq X, Hewinson J, Iyer V, Merchant W, Elliott F, Harland M, Bishop DT, Newton-Bishop JA, Adams DJ. O'Shea SJ, et al. Among authors: jacq x. Hum Mol Genet. 2017 Feb 15;26(4):717-728. doi: 10.1093/hmg/ddw403. Hum Mol Genet. 2017. PMID: 28062663 Free PMC article.
Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells.
Colland F, Formstecher E, Jacq X, Reverdy C, Planquette C, Conrath S, Trouplin V, Bianchi J, Aushev VN, Camonis J, Calabrese A, Borg-Capra C, Sippl W, Collura V, Boissy G, Rain JC, Guedat P, Delansorne R, Daviet L. Colland F, et al. Among authors: jacq x. Mol Cancer Ther. 2009 Aug;8(8):2286-95. doi: 10.1158/1535-7163.MCT-09-0097. Epub 2009 Aug 11. Mol Cancer Ther. 2009. PMID: 19671755
Functional proteomics mapping of a human signaling pathway.
Colland F, Jacq X, Trouplin V, Mougin C, Groizeleau C, Hamburger A, Meil A, Wojcik J, Legrain P, Gauthier JM. Colland F, et al. Among authors: jacq x. Genome Res. 2004 Jul;14(7):1324-32. doi: 10.1101/gr.2334104. Genome Res. 2004. PMID: 15231748 Free PMC article.
22 results