Jacobson KA - Search Results

1

Stereocontrolled access to thioisosteres of nucleoside di- and triphosphates.

Zhang HJ, Ociepa M, Nassir M, Zheng B, Lewicki SA, Salmaso V, Baburi H, Nagel J, Mirza S, Bueschbell B, Al-Hroub H, Perzanowska O, Lin Z, Schmidt MA, Eastgate MD, Jacobson KA, Müller CE, Kowalska J, Jemielity J, Baran PS. Zhang HJ, et al. Among authors: jacobson ka. Nat Chem. 2024 Feb;16(2):249-258. doi: 10.1038/s41557-023-01347-2. Epub 2023 Oct 19. Nat Chem. 2024. PMID: 37857844

2

Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors.

Jacobson KA, Shi D, Gallo-Rodriguez C, Manning M Jr, Müller C, Daly JW, Neumeyer JL, Kiriasis L, Pfleiderer W. Jacobson KA, et al. J Med Chem. 1993 Sep 3;36(18):2639-44. doi: 10.1021/jm00070a007. J Med Chem. 1993. PMID: 8410976

3

Allosteric modulation of A(3) adenosine receptors by a series of 3-(2-pyridinyl)isoquinoline derivatives.

Gao ZG, Van Muijlwijk-Koezen JE, Chen A, Müller CE, Ijzerman AP, Jacobson KA. Gao ZG, et al. Among authors: jacobson ka. Mol Pharmacol. 2001 Nov;60(5):1057-63. Mol Pharmacol. 2001. PMID: 11641434 Free PMC article.

4

Identification by site-directed mutagenesis of residues involved in ligand recognition and activation of the human A3 adenosine receptor.

Gao ZG, Chen A, Barak D, Kim SK, Müller CE, Jacobson KA. Gao ZG, et al. Among authors: jacobson ka. J Biol Chem. 2002 May 24;277(21):19056-63. doi: 10.1074/jbc.M110960200. Epub 2002 Mar 12. J Biol Chem. 2002. PMID: 11891221 Free PMC article.

5

Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.

Kim SA, Marshall MA, Melman N, Kim HS, Müller CE, Linden J, Jacobson KA. Kim SA, et al. Among authors: jacobson ka. J Med Chem. 2002 May 23;45(11):2131-8. doi: 10.1021/jm0104318. J Med Chem. 2002. PMID: 12014951 Free PMC article.

6

Imidazo[2,1-i]purin-5-ones and related tricyclic water-soluble purine derivatives: potent A(2A)- and A(3)-adenosine receptor antagonists.

Müller CE, Thorand M, Qurishi R, Diekmann M, Jacobson KA, Padgett WL, Daly JW. Müller CE, et al. Among authors: jacobson ka. J Med Chem. 2002 Aug 1;45(16):3440-50. doi: 10.1021/jm011093d. J Med Chem. 2002. PMID: 12139454 Free PMC article.

7

2-Phenylimidazo[2,1-i]purin-5-ones: structure-activity relationships and characterization of potent and selective inverse agonists at Human A3 adenosine receptors.

Ozola V, Thorand M, Diekmann M, Qurishi R, Schumacher B, Jacobson KA, Müller CE. Ozola V, et al. Among authors: jacobson ka. Bioorg Med Chem. 2003 Feb 6;11(3):347-56. doi: 10.1016/s0968-0896(02)00456-x. Bioorg Med Chem. 2003. PMID: 12517430 Free PMC article.

8

Differential allosteric modulation by amiloride analogues of agonist and antagonist binding at A(1) and A(3) adenosine receptors.

Gao ZG, Melman N, Erdmann A, Kim SG, Müller CE, IJzerman AP, Jacobson KA. Gao ZG, et al. Among authors: jacobson ka. Biochem Pharmacol. 2003 Feb 15;65(4):525-34. doi: 10.1016/s0006-2952(02)01556-3. Biochem Pharmacol. 2003. PMID: 12566079 Free PMC article.

9

Xanthines as adenosine receptor antagonists.

Müller CE, Jacobson KA. Müller CE, et al. Among authors: jacobson ka. Handb Exp Pharmacol. 2011;(200):151-99. doi: 10.1007/978-3-642-13443-2_6. Handb Exp Pharmacol. 2011. PMID: 20859796 Free PMC article. Review.

10

Recent developments in adenosine receptor ligands and their potential as novel drugs.

Müller CE, Jacobson KA. Müller CE, et al. Among authors: jacobson ka. Biochim Biophys Acta. 2011 May;1808(5):1290-308. doi: 10.1016/j.bbamem.2010.12.017. Epub 2010 Dec 23. Biochim Biophys Acta. 2011. PMID: 21185259 Free PMC article. Review.

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