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The DHODH inhibitor PTC299 arrests SARS-CoV-2 replication and suppresses induction of inflammatory cytokines.
Luban J, Sattler RA, Mühlberger E, Graci JD, Cao L, Weetall M, Trotta C, Colacino JM, Bavari S, Strambio-De-Castillia C, Suder EL, Wang Y, Soloveva V, Cintron-Lue K, Naryshkin NA, Pykett M, Welch EM, O'Keefe K, Kong R, Goodwin E, Jacobson A, Paessler S, Peltz SW. Luban J, et al. Among authors: jacobson a. Virus Res. 2021 Jan 15;292:198246. doi: 10.1016/j.virusres.2020.198246. Epub 2020 Nov 26. Virus Res. 2021. PMID: 33249060 Free PMC article.
Turnover of mRNA in prokaryotes and lower eukaryotes.
Higgins CF, Peltz SW, Jacobson A. Higgins CF, et al. Among authors: jacobson a. Curr Opin Genet Dev. 1992 Oct;2(5):739-47. doi: 10.1016/s0959-437x(05)80134-0. Curr Opin Genet Dev. 1992. PMID: 1281028 Review.
A mutation in the tRNA nucleotidyltransferase gene promotes stabilization of mRNAs in Saccharomyces cerevisiae.
Peltz SW, Donahue JL, Jacobson A. Peltz SW, et al. Among authors: jacobson a. Mol Cell Biol. 1992 Dec;12(12):5778-84. doi: 10.1128/mcb.12.12.5778-5784.1992. Mol Cell Biol. 1992. PMID: 1448105 Free PMC article.
To identify trans-acting factors involved in mRNA decay in the yeast Saccharomyces cerevisiae, we have begun to characterize conditional lethal mutants that affect mRNA steady-state levels. A screen of a collection of temperature-sensitive mutants identified ts352, …
To identify trans-acting factors involved in mRNA decay in the yeast Saccharomyces cerevisiae, we have begun to characterize conditional let …
mRNA stability: in trans-it.
Peltz SW, Jacobson A. Peltz SW, et al. Among authors: jacobson a. Curr Opin Cell Biol. 1992 Dec;4(6):979-83. doi: 10.1016/0955-0674(92)90129-z. Curr Opin Cell Biol. 1992. PMID: 1485969 Review.
Nonsense-mediated mRNA decay in yeast.
Peltz SW, He F, Welch E, Jacobson A. Peltz SW, et al. Among authors: jacobson a. Prog Nucleic Acid Res Mol Biol. 1994;47:271-98. doi: 10.1016/s0079-6603(08)60254-8. Prog Nucleic Acid Res Mol Biol. 1994. PMID: 8016322 Review. No abstract available.
1,766 results