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Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.
Mills EL, Kelly B, Logan A, Costa ASH, Varma M, Bryant CE, Tourlomousis P, Däbritz JHM, Gottlieb E, Latorre I, Corr SC, McManus G, Ryan D, Jacobs HT, Szibor M, Xavier RJ, Braun T, Frezza C, Murphy MP, O'Neill LA. Mills EL, et al. Among authors: jacobs ht. Cell. 2016 Oct 6;167(2):457-470.e13. doi: 10.1016/j.cell.2016.08.064. Epub 2016 Sep 22. Cell. 2016. PMID: 27667687 Free PMC article.
Expression of the Ciona intestinalis alternative oxidase (AOX) in Drosophila complements defects in mitochondrial oxidative phosphorylation.
Fernandez-Ayala DJ, Sanz A, Vartiainen S, Kemppainen KK, Babusiak M, Mustalahti E, Costa R, Tuomela T, Zeviani M, Chung J, O'Dell KM, Rustin P, Jacobs HT. Fernandez-Ayala DJ, et al. Among authors: jacobs ht. Cell Metab. 2009 May;9(5):449-60. doi: 10.1016/j.cmet.2009.03.004. Cell Metab. 2009. PMID: 19416715 Free article.
Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology.
Szibor M, Dhandapani PK, Dufour E, Holmström KM, Zhuang Y, Salwig I, Wittig I, Heidler J, Gizatullina Z, Gainutdinov T; German Mouse Clinic Consortium; Fuchs H, Gailus-Durner V, de Angelis MH, Nandania J, Velagapudi V, Wietelmann A, Rustin P, Gellerich FN, Jacobs HT, Braun T. Szibor M, et al. Among authors: jacobs ht. Dis Model Mech. 2017 Feb 1;10(2):163-171. doi: 10.1242/dmm.027839. Epub 2016 Dec 14. Dis Model Mech. 2017. PMID: 28067626 Free PMC article.
Perturbed Redox Signaling Exacerbates a Mitochondrial Myopathy.
Dogan SA, Cerutti R, Benincá C, Brea-Calvo G, Jacobs HT, Zeviani M, Szibor M, Viscomi C. Dogan SA, et al. Among authors: jacobs ht. Cell Metab. 2018 Nov 6;28(5):764-775.e5. doi: 10.1016/j.cmet.2018.07.012. Epub 2018 Aug 16. Cell Metab. 2018. PMID: 30122554 Free PMC article.
Alternative Oxidase Attenuates Cigarette Smoke-induced Lung Dysfunction and Tissue Damage.
Giordano L, Farnham A, Dhandapani PK, Salminen L, Bhaskaran J, Voswinckel R, Rauschkolb P, Scheibe S, Sommer N, Beisswenger C, Weissmann N, Braun T, Jacobs HT, Bals R, Herr C, Szibor M. Giordano L, et al. Among authors: jacobs ht. Am J Respir Cell Mol Biol. 2019 May;60(5):515-522. doi: 10.1165/rcmb.2018-0261OC. Am J Respir Cell Mol Biol. 2019. PMID: 30339461 Free PMC article.
Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy.
Rajendran J, Purhonen J, Tegelberg S, Smolander OP, Mörgelin M, Rozman J, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Auvinen P, Mervaala E, Jacobs HT, Szibor M, Fellman V, Kallijärvi J. Rajendran J, et al. Among authors: jacobs ht. EMBO Mol Med. 2019 Jan;11(1):e9456. doi: 10.15252/emmm.201809456. EMBO Mol Med. 2019. PMID: 30530468 Free PMC article.
180 results