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Microbial rhodoquinone biosynthesis proceeds via an atypical RquA-catalyzed amino transfer from S-adenosyl-L-methionine to ubiquinone.
Neupane T, Chambers LR, Godfrey AJ, Monlux MM, Jacobs EJ, Whitworth S, Spawn JE, Clingman SHK, Vergunst KL, Niven FM, Townley JJ, Orion IW, Goodspeed CR, Cooper KA, Cronk JD, Shepherd JN, Langelaan DN. Neupane T, et al. Among authors: jacobs ej. Commun Chem. 2022 Aug 1;5(1):89. doi: 10.1038/s42004-022-00711-6. Commun Chem. 2022. PMID: 36697674 Free PMC article.
Recombinant RquA catalyzes the in vivo conversion of ubiquinone to rhodoquinone in Escherichia coli and Saccharomyces cerevisiae.
Bernert AC, Jacobs EJ, Reinl SR, Choi CCY, Roberts Buceta PM, Culver JC, Goodspeed CR, Bradley MC, Clarke CF, Basset GJ, Shepherd JN. Bernert AC, et al. Among authors: jacobs ej. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Sep;1864(9):1226-1234. doi: 10.1016/j.bbalip.2019.05.007. Epub 2019 May 21. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 31121262 Free PMC article.
Prospective associations of hemoglobin A1c and c-peptide with risk of diabetes-related cancers in the Cancer Prevention Study-II Nutrition Cohort.
Campbell PT, Newton CC, Jacobs EJ, McCullough ML, Wang Y, Rees-Punia E, Guinter MA, Murphy N, Koshiol J, Dehal AN, Rohan T, Strickler H, Petrick J, Gunter M, Zhang X, McGlynn KA, Pollak M, Patel AV, Gapstur SM. Campbell PT, et al. Among authors: jacobs ej. Cancer Res Commun. 2022 Jul;2(7):653-662. doi: 10.1158/2767-9764.crc-22-0082. Epub 2022 Jul 14. Cancer Res Commun. 2022. PMID: 36712480 Free PMC article.
241 results