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Obesity-Linked PPARγ S273 Phosphorylation Promotes Insulin Resistance through Growth Differentiation Factor 3.
Hall JA, Ramachandran D, Roh HC, DiSpirito JR, Belchior T, Zushin PH, Palmer C, Hong S, Mina AI, Liu B, Deng Z, Aryal P, Jacobs C, Tenen D, Brown CW, Charles JF, Shulman GI, Kahn BB, Tsai LTY, Rosen ED, Spiegelman BM, Banks AS. Hall JA, et al. Among authors: jacobs c. Cell Metab. 2020 Oct 6;32(4):665-675.e6. doi: 10.1016/j.cmet.2020.08.016. Epub 2020 Sep 16. Cell Metab. 2020. PMID: 32941798 Free PMC article.
NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor.
Mendoza A, Astapova I, Shimizu H, Gallop MR, Al-Sowaimel L, MacGowan SMD, Bergmann T, Berg AH, Tenen DE, Jacobs C, Lyubetskaya A, Tsai L, Hollenberg AN. Mendoza A, et al. Among authors: jacobs c. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8458-E8467. doi: 10.1073/pnas.1706917114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923959 Free PMC article.
Neurotensin is an anti-thermogenic peptide produced by lymphatic endothelial cells.
Li J, Li E, Czepielewski RS, Chi J, Guo X, Han YH, Wang D, Wang L, Hu B, Dawes B, Jacobs C, Tenen D, Lin SJ, Lee B, Morris D, Tobias A, Randolph GJ, Cohen P, Tsai L, Rosen ED. Li J, et al. Among authors: jacobs c. Cell Metab. 2021 Jul 6;33(7):1449-1465.e6. doi: 10.1016/j.cmet.2021.04.019. Epub 2021 May 25. Cell Metab. 2021. PMID: 34038712 Free PMC article.
Mesothelial cells are not a source of adipocytes in mice.
Westcott GP, Emont MP, Li J, Jacobs C, Tsai L, Rosen ED. Westcott GP, et al. Among authors: jacobs c. Cell Rep. 2021 Jul 13;36(2):109388. doi: 10.1016/j.celrep.2021.109388. Cell Rep. 2021. PMID: 34260927 Free PMC article.
Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP.
Mendoza A, Tang C, Choi J, Acuña M, Logan M, Martin AG, Al-Sowaimel L, Desai BN, Tenen DE, Jacobs C, Lyubetskaya A, Fu Y, Liu H, Tsai L, Cohen DE, Forrest D, Wilson AA, Hollenberg AN. Mendoza A, et al. Among authors: jacobs c. Sci Signal. 2021 Nov 16;14(709):eabh3839. doi: 10.1126/scisignal.abh3839. Epub 2021 Nov 16. Sci Signal. 2021. PMID: 34784250 Free PMC article.
A single-cell atlas of human and mouse white adipose tissue.
Emont MP, Jacobs C, Essene AL, Pant D, Tenen D, Colleluori G, Di Vincenzo A, Jørgensen AM, Dashti H, Stefek A, McGonagle E, Strobel S, Laber S, Agrawal S, Westcott GP, Kar A, Veregge ML, Gulko A, Srinivasan H, Kramer Z, De Filippis E, Merkel E, Ducie J, Boyd CG, Gourash W, Courcoulas A, Lin SJ, Lee BT, Morris D, Tobias A, Khera AV, Claussnitzer M, Pers TH, Giordano A, Ashenberg O, Regev A, Tsai LT, Rosen ED. Emont MP, et al. Among authors: jacobs c. Nature. 2022 Mar;603(7903):926-933. doi: 10.1038/s41586-022-04518-2. Epub 2022 Mar 16. Nature. 2022. PMID: 35296864 Free PMC article.
Author Correction: A single-cell atlas of human and mouse white adipose tissue.
Emont MP, Jacobs C, Essene AL, Pant D, Tenen D, Colleluori G, Di Vincenzo A, Jørgensen AM, Dashti H, Stefek A, McGonagle E, Strobel S, Laber S, Agrawal S, Westcott GP, Kar A, Veregge ML, Gulko A, Srinivasan H, Kramer Z, De Filippis E, Merkel E, Ducie J, Boyd CG, Gourash W, Courcoulas A, Lin SJ, Lee BT, Morris D, Tobias A, Khera AV, Claussnitzer M, Pers TH, Giordano A, Ashenberg O, Regev A, Tsai LT, Rosen ED. Emont MP, et al. Among authors: jacobs c. Nature. 2023 Aug;620(7973):E14. doi: 10.1038/s41586-023-06445-2. Nature. 2023. PMID: 37495702 No abstract available.
1,868 results