Jacob RA - Search Results

1

Identification of Novel Subcellular Localization and Trafficking of HIV-1 Nef Variants from Reference Strains G (F1.93.HH8793) and H (BE.93.VI997).

Van Nynatten LR, Johnson AL, Dirk BS, Pawlak EN, Jacob RA, Haeryfar SMM, Dikeakos JD. Van Nynatten LR, et al. Among authors: jacob ra. Viruses. 2018 Sep 13;10(9):493. doi: 10.3390/v10090493. Viruses. 2018. PMID: 30217018 Free PMC article.

2

HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling.

Dirk BS, Pawlak EN, Johnson AL, Van Nynatten LR, Jacob RA, Heit B, Dikeakos JD. Dirk BS, et al. Among authors: jacob ra. Sci Rep. 2016 Nov 14;6:37021. doi: 10.1038/srep37021. Sci Rep. 2016. PMID: 27841315 Free PMC article.

3

Viral bimolecular fluorescence complementation: a novel tool to study intracellular vesicular trafficking pathways.

Dirk BS, Jacob RA, Johnson AL, Pawlak EN, Cavanagh PC, Van Nynatten L, Haeryfar SM, Dikeakos JD. Dirk BS, et al. Among authors: jacob ra. PLoS One. 2015 Apr 27;10(4):e0125619. doi: 10.1371/journal.pone.0125619. eCollection 2015. PLoS One. 2015. PMID: 25915798 Free PMC article.

4

The interaction between HIV-1 Nef and adaptor protein-2 reduces Nef-mediated CD4⁺ T cell apoptosis.

Jacob RA, Johnson AL, Pawlak EN, Dirk BS, Van Nynatten LR, Haeryfar SMM, Dikeakos JD. Jacob RA, et al. Virology. 2017 Sep;509:1-10. doi: 10.1016/j.virol.2017.05.018. Epub 2017 Jun 1. Virology. 2017. PMID: 28577469 Free article.

5

The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4⁺ T cells.

Pawlak EN, Dirk BS, Jacob RA, Johnson AL, Dikeakos JD. Pawlak EN, et al. Among authors: jacob ra. Retrovirology. 2018 Jan 12;15(1):6. doi: 10.1186/s12977-018-0388-3. Retrovirology. 2018. PMID: 29329537 Free PMC article.

6

The HIV-1 accessory protein Nef increases surface expression of the checkpoint receptor Tim-3 in infected CD4⁺ T cells.

Jacob RA, Edgar CR, Prévost J, Trothen SM, Lurie A, Mumby MJ, Galbraith A, Kirchhoff F, Haeryfar SMM, Finzi A, Dikeakos JD. Jacob RA, et al. J Biol Chem. 2021 Sep;297(3):101042. doi: 10.1016/j.jbc.2021.101042. Epub 2021 Aug 4. J Biol Chem. 2021. PMID: 34358561 Free PMC article.

7

PACS-1 and adaptor protein-1 mediate ACTH trafficking to the regulated secretory pathway.

Dirk BS, End C, Pawlak EN, Van Nynatten LR, Jacob RA, Heit B, Dikeakos JD. Dirk BS, et al. Among authors: jacob ra. Biochem Biophys Res Commun. 2018 Dec 9;507(1-4):519-525. doi: 10.1016/j.bbrc.2018.11.085. Epub 2018 Nov 17. Biochem Biophys Res Commun. 2018. PMID: 30458990

8

HIV-1 Vpu Downregulates Tim-3 from the Surface of Infected CD4⁺ T Cells.

Prévost J, Edgar CR, Richard J, Trothen SM, Jacob RA, Mumby MJ, Pickering S, Dubé M, Kaufmann DE, Kirchhoff F, Neil SJD, Finzi A, Dikeakos JD. Prévost J, et al. Among authors: jacob ra. J Virol. 2020 Mar 17;94(7):e01999-19. doi: 10.1128/JVI.01999-19. Print 2020 Mar 17. J Virol. 2020. PMID: 31941771 Free PMC article.

9

Efferocytic Defects in Early Atherosclerosis Are Driven by GATA2 Overexpression in Macrophages.

Yin C, Vrieze AM, Rosoga M, Akingbasote J, Pawlak EN, Jacob RA, Hu J, Sharma N, Dikeakos JD, Barra L, Nagpal AD, Heit B. Yin C, et al. Among authors: jacob ra. Front Immunol. 2020 Oct 23;11:594136. doi: 10.3389/fimmu.2020.594136. eCollection 2020. Front Immunol. 2020. PMID: 33193444 Free PMC article.

10

Roadmap for Connecting Cancer Rehabilitation With Survivorship to Improve Patient Outcomes and Clinical Efficiency.

Alfano CM, Pugh TM, Tortorella B, Jacob RA, Mitchell CH, Raj VS. Alfano CM, et al. Among authors: jacob ra. Am J Phys Med Rehabil. 2024 Mar 1;103(3S Suppl 1):S10-S15. doi: 10.1097/PHM.0000000000002373. Am J Phys Med Rehabil. 2024. PMID: 38364024

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