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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2004 1
2005 1
2006 4
2007 2
2008 3
2009 2
2010 5
2011 7
2012 8
2013 3
2014 1
2024 0

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33 results

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Page 1
Data-driven medicinal chemistry in the era of big data.
Lusher SJ, McGuire R, van Schaik RC, Nicholson CD, de Vlieg J. Lusher SJ, et al. Among authors: de vlieg j. Drug Discov Today. 2014 Jul;19(7):859-68. doi: 10.1016/j.drudis.2013.12.004. Epub 2013 Dec 17. Drug Discov Today. 2014. PMID: 24361338 Review.
Prednisolone induces the Wnt signalling pathway in 3T3-L1 adipocytes.
Fleuren WW, Linssen MM, Toonen EJ, van der Zon GC, Guigas B, de Vlieg J, Dokter WH, Ouwens DM, Alkema W. Fleuren WW, et al. Among authors: de vlieg j. Arch Physiol Biochem. 2013 May;119(2):52-64. doi: 10.3109/13813455.2013.774022. Epub 2013 Mar 19. Arch Physiol Biochem. 2013. PMID: 23506355 Free PMC article.
Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index.
van Lierop MJ, Alkema W, Laskewitz AJ, Dijkema R, van der Maaden HM, Smit MJ, Plate R, Conti PG, Jans CG, Timmers CM, van Boeckel CA, Lusher SJ, McGuire R, van Schaik RC, de Vlieg J, Smeets RL, Hofstra CL, Boots AM, van Duin M, Ingelse BA, Schoonen WG, Grefhorst A, van Dijk TH, Kuipers F, Dokter WH. van Lierop MJ, et al. Among authors: de vlieg j. PLoS One. 2012;7(11):e48385. doi: 10.1371/journal.pone.0048385. Epub 2012 Nov 12. PLoS One. 2012. PMID: 23152771 Free PMC article.
Comparative analysis of pharmacophore screening tools.
Sanders MP, Barbosa AJ, Zarzycka B, Nicolaes GA, Klomp JP, de Vlieg J, Del Rio A. Sanders MP, et al. Among authors: de vlieg j. J Chem Inf Model. 2012 Jun 25;52(6):1607-20. doi: 10.1021/ci2005274. Epub 2012 Jun 13. J Chem Inf Model. 2012. PMID: 22646988
A prospective cross-screening study on G-protein-coupled receptors: lessons learned in virtual compound library design.
Sanders MP, Roumen L, van der Horst E, Lane JR, Vischer HF, van Offenbeek J, de Vries H, Verhoeven S, Chow KY, Verkaar F, Beukers MW, McGuire R, Leurs R, Ijzerman AP, de Vlieg J, de Esch IJ, Zaman GJ, Klomp JP, Bender A, de Graaf C. Sanders MP, et al. Among authors: de vlieg j. J Med Chem. 2012 Jun 14;55(11):5311-25. doi: 10.1021/jm300280e. Epub 2012 May 23. J Med Chem. 2012. PMID: 22563707
X-ray structures of progesterone receptor ligand binding domain in its agonist state reveal differing mechanisms for mixed profiles of 11β-substituted steroids.
Lusher SJ, Raaijmakers HC, Vu-Pham D, Kazemier B, Bosch R, McGuire R, Azevedo R, Hamersma H, Dechering K, Oubrie A, van Duin M, de Vlieg J. Lusher SJ, et al. Among authors: de vlieg j. J Biol Chem. 2012 Jun 8;287(24):20333-43. doi: 10.1074/jbc.M111.308403. Epub 2012 Apr 25. J Biol Chem. 2012. PMID: 22535964 Free PMC article.
33 results