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COVID-19 therapy: What weapons do we bring into battle?
Bioorg Med Chem. 2020 Dec 1;28(23):115757. doi: 10.1016/j.bmc.2020.115757. Epub 2020 Sep 10.
Bioorg Med Chem. 2020.
PMID: 32992245
Free PMC article.
Synthesis, in vitro and in vivo biological evaluation, COX-1/2 inhibition and molecular docking study of indole-N-acylhydrazone derivatives.
Moraes ADTO, Miranda MDS, Jacob ÍTT, Amorim CADC, Moura RO, Silva SÂSD, Soares MBP, Almeida SMV, Souza TRCL, Oliveira JF, Silva TGD, Melo CML, Moreira DRM, Lima MDCA.
Moraes ADTO, et al. Among authors: jacob itt.
Bioorg Med Chem. 2018 Nov 1;26(20):5388-5396. doi: 10.1016/j.bmc.2018.07.024. Epub 2018 Jul 17.
Bioorg Med Chem. 2018.
PMID: 30293795
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Pectin-like polysaccharide extracted from leaves Crataeva tapia promotes antioxidant, immunomodulatory and emulsifiers applied in therapeutic formulations.
da Paz Leôncio Alves S, Jacob ITT, Arruda MDM, da Silva AR, de Sousa GF, de Souza GA, de Lima MDCA, de Souza IA, de Melo CML, da Cruz Filho IJ, do Nascimento Santos DKD.
da Paz Leôncio Alves S, et al. Among authors: jacob itt.
3 Biotech. 2023 Apr;13(4):114. doi: 10.1007/s13205-023-03509-y. Epub 2023 Mar 9.
3 Biotech. 2023.
PMID: 36909979
Free PMC article.
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Thiazolidine derivatives: In vitro toxicity assessment against promastigote and amastigote forms of Leishmania infantum and ultrastructural study.
Gouveia ALA, Santos FAB, Alves LC, Cruz-Filho IJ, Silva PR, Jacob ITT, Soares JCS, Santos DKDN, Souza TRCL, Oliveira JF, Lima MDCA.
Gouveia ALA, et al. Among authors: jacob itt.
Exp Parasitol. 2022 May-Jun;236-237:108253. doi: 10.1016/j.exppara.2022.108253. Epub 2022 Apr 4.
Exp Parasitol. 2022.
PMID: 35381223
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Anti-inflammatory activity of novel thiosemicarbazone compounds indole-based as COX inhibitors.
Jacob ÍTT, Gomes FOS, de Miranda MDS, de Almeida SMV, da Cruz-Filho IJ, Peixoto CA, da Silva TG, Moreira DRM, de Melo CML, de Oliveira JF, de Lima MCA.
Jacob ÍTT, et al.
Pharmacol Rep. 2021 Jun;73(3):907-925. doi: 10.1007/s43440-021-00221-7. Epub 2021 Feb 15.
Pharmacol Rep. 2021.
PMID: 33590474
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Synthesis and Anticancer Evaluation of Thiazacridine Derivatives Reveals New Selective Molecules to Hematopoietic Neoplastic Cells.
de Melo Rego MJB, de Sena WLB, de Moura RO, Jacob ITT, Lins E Lins TU, Pereira MC, do Carmo A Lima M, Galdino-Pitta MR, da R Pitta I, da Rocha Pitta MG.
de Melo Rego MJB, et al. Among authors: jacob itt.
Comb Chem High Throughput Screen. 2017;20(8):713-718. doi: 10.2174/1386207320666170724114802.
Comb Chem High Throughput Screen. 2017.
PMID: 28738767
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