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Reengineering the specificity of the highly selective Clostridium botulinum protease via directed evolution.
Sci Rep. 2022 Jun 15;12(1):9956. doi: 10.1038/s41598-022-13617-z.
Sci Rep. 2022.
PMID: 35705606
Free PMC article.
OnabotulinumtoxinA Displays Greater Biological Activity Compared to IncobotulinumtoxinA, Demonstrating Non-Interchangeability in Both In Vitro and In Vivo Assays.
Rupp D, Nicholson G, Canty D, Wang J, Rhéaume C, Le L, Steward LE, Washburn M, Jacky BP, Broide RS, Philipp-Dormston WG, Brin MF, Brideau-Andersen A.
Rupp D, et al.
Toxins (Basel). 2020 Jun 13;12(6):393. doi: 10.3390/toxins12060393.
Toxins (Basel). 2020.
PMID: 32545832
Free PMC article.
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Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A).
Jacky BP, Garay PE, Dupuy J, Nelson JB, Cai B, Molina Y, Wang J, Steward LE, Broide RS, Francis J, Aoki KR, Stevens RC, Fernández-Salas E.
Jacky BP, et al.
PLoS Pathog. 2013;9(5):e1003369. doi: 10.1371/journal.ppat.1003369. Epub 2013 May 16.
PLoS Pathog. 2013.
PMID: 23696738
Free PMC article.
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Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay.
Fernández-Salas E, Wang J, Molina Y, Nelson JB, Jacky BP, Aoki KR.
Fernández-Salas E, et al.
PLoS One. 2012;7(11):e49516. doi: 10.1371/journal.pone.0049516. Epub 2012 Nov 21.
PLoS One. 2012.
PMID: 23185348
Free PMC article.
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Preventive, Cumulative Effects of Botulinum Toxin Type A in Facial Aesthetics.
Humphrey S, Jacky B, Gallagher CJ.
Humphrey S, et al.
Dermatol Surg. 2017 Dec;43 Suppl 3:S244-S251. doi: 10.1097/DSS.0000000000001404.
Dermatol Surg. 2017.
PMID: 33065950
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PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions.
Møller TC, Wirth VF, Roberts NI, Bender J, Bach A, Jacky BP, Strømgaard K, Deussing JM, Schwartz TW, Martinez KL.
Møller TC, et al.
PLoS One. 2013 May 14;8(5):e63352. doi: 10.1371/journal.pone.0063352. Print 2013.
PLoS One. 2013.
PMID: 23691031
Free PMC article.
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