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IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy.
Zhou T, Damsky W, Weizman OE, McGeary MK, Hartmann KP, Rosen CE, Fischer S, Jackson R, Flavell RA, Wang J, Sanmamed MF, Bosenberg MW, Ring AM. Zhou T, et al. Among authors: jackson r. Nature. 2020 Jul;583(7817):609-614. doi: 10.1038/s41586-020-2422-6. Epub 2020 Jun 24. Nature. 2020. PMID: 32581358 Free PMC article.
Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis.
Nowarski R, Jackson R, Gagliani N, de Zoete MR, Palm NW, Bailis W, Low JS, Harman CC, Graham M, Elinav E, Flavell RA. Nowarski R, et al. Among authors: jackson r. Cell. 2015 Dec 3;163(6):1444-56. doi: 10.1016/j.cell.2015.10.072. Cell. 2015. PMID: 26638073 Free PMC article.
The translation of non-canonical open reading frames controls mucosal immunity.
Jackson R, Kroehling L, Khitun A, Bailis W, Jarret A, York AG, Khan OM, Brewer JR, Skadow MH, Duizer C, Harman CCD, Chang L, Bielecki P, Solis AG, Steach HR, Slavoff S, Flavell RA. Jackson R, et al. Nature. 2018 Dec;564(7736):434-438. doi: 10.1038/s41586-018-0794-7. Epub 2018 Dec 12. Nature. 2018. PMID: 30542152 Free PMC article.
Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function.
Bailis W, Shyer JA, Zhao J, Canaveras JCG, Al Khazal FJ, Qu R, Steach HR, Bielecki P, Khan O, Jackson R, Kluger Y, Maher LJ 3rd, Rabinowitz J, Craft J, Flavell RA. Bailis W, et al. Among authors: jackson r. Nature. 2019 Jul;571(7765):403-407. doi: 10.1038/s41586-019-1311-3. Epub 2019 Jun 19. Nature. 2019. PMID: 31217581 Free PMC article.
Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity.
Jarret A, Jackson R, Duizer C, Healy ME, Zhao J, Rone JM, Bielecki P, Sefik E, Roulis M, Rice T, Sivanathan KN, Zhou T, Solis AG, Honcharova-Biletska H, Vélez K, Hartner S, Low JS, Qu R, de Zoete MR, Palm NW, Ring AM, Weber A, Moor AE, Kluger Y, Nowarski R, Flavell RA. Jarret A, et al. Among authors: jackson r. Cell. 2020 Jan 9;180(1):50-63.e12. doi: 10.1016/j.cell.2019.12.016. Cell. 2020. PMID: 31923399 Free PMC article.
The induction and function of the anti-inflammatory fate of TH17 cells.
Xu H, Agalioti T, Zhao J, Steglich B, Wahib R, Vesely MCA, Bielecki P, Bailis W, Jackson R, Perez D, Izbicki J, Licona-Limón P, Kaartinen V, Geginat J, Esplugues E, Tolosa E, Huber S, Flavell RA, Gagliani N. Xu H, et al. Among authors: jackson r. Nat Commun. 2020 Jul 3;11(1):3334. doi: 10.1038/s41467-020-17097-5. Nat Commun. 2020. PMID: 32620760 Free PMC article.
Skin-resident innate lymphoid cells converge on a pathogenic effector state.
Bielecki P, Riesenfeld SJ, Hütter JC, Torlai Triglia E, Kowalczyk MS, Ricardo-Gonzalez RR, Lian M, Amezcua Vesely MC, Kroehling L, Xu H, Slyper M, Muus C, Ludwig LS, Christian E, Tao L, Kedaigle AJ, Steach HR, York AG, Skadow MH, Yaghoubi P, Dionne D, Jarret A, McGee HM, Porter CBM, Licona-Limón P, Bailis W, Jackson R, Gagliani N, Gasteiger G, Locksley RM, Regev A, Flavell RA. Bielecki P, et al. Among authors: jackson r. Nature. 2021 Apr;592(7852):128-132. doi: 10.1038/s41586-021-03188-w. Epub 2021 Feb 3. Nature. 2021. PMID: 33536623 Free PMC article.
Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity.
Solis AG, Bielecki P, Steach HR, Sharma L, Harman CCD, Yun S, de Zoete MR, Warnock JN, To SDF, York AG, Mack M, Schwartz MA, Dela Cruz CS, Palm NW, Jackson R, Flavell RA. Solis AG, et al. Among authors: jackson r. Nature. 2019 Sep;573(7772):69-74. doi: 10.1038/s41586-019-1485-8. Epub 2019 Aug 21. Nature. 2019. PMID: 31435009 Free PMC article.
5,447 results