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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 2
2003 1
2004 3
2005 4
2006 3
2007 8
2008 5
2009 2
2010 6
2011 6
2012 7
2013 8
2014 10
2015 7
2016 6
2017 10
2018 6
2019 9
2020 6
2021 8
2022 6
2023 8
2024 2

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119 results

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Page 1
PM534, an Optimized Target-Protein Interaction Strategy through the Colchicine Site of Tubulin.
Lucena-Agell D, Guillén MJ, Matesanz R, Álvarez-Bernad B, Hortigüela R, Avilés P, Martínez-Díez M, Santamaría-Núñez G, Contreras J, Plaza-Menacho I, Giménez-Abián JF, Oliva MA, Cuevas C, Díaz JF. Lucena-Agell D, et al. Among authors: diaz jf. J Med Chem. 2024 Feb 22;67(4):2619-2630. doi: 10.1021/acs.jmedchem.3c01775. Epub 2024 Jan 31. J Med Chem. 2024. PMID: 38294341 Free PMC article.
Modulation of taxane binding to tubulin curved and straight conformations by systematic 3'N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency.
Ma Y, Josa-Prado F, Essif JN, Liu S, Li S, Lucena-Agell D, Chan PY, Goossens K, Hortigüela R, Matesanz R, Wang Y, Gago F, Wang H, Risinger A, Diaz JF, Fang WS. Ma Y, et al. Among authors: diaz jf. Eur J Med Chem. 2023 Nov 5;259:115668. doi: 10.1016/j.ejmech.2023.115668. Epub 2023 Jul 19. Eur J Med Chem. 2023. PMID: 37490800
Structural insight into the stabilization of microtubules by taxanes.
Prota AE, Lucena-Agell D, Ma Y, Estevez-Gallego J, Li S, Bargsten K, Josa-Prado F, Altmann KH, Gaillard N, Kamimura S, Mühlethaler T, Gago F, Oliva MA, Steinmetz MO, Fang WS, Díaz JF. Prota AE, et al. Among authors: diaz jf. Elife. 2023 Mar 6;12:e84791. doi: 10.7554/eLife.84791. Elife. 2023. PMID: 36876916 Free PMC article.
Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics.
Boiarska Z, Pérez-Peña H, Abel AC, Marzullo P, Álvarez-Bernad B, Bonato F, Santini B, Horvath D, Lucena-Agell D, Vasile F, Sironi M, Díaz JF, Prota AE, Pieraccini S, Passarella D. Boiarska Z, et al. Among authors: diaz jf. Chemistry. 2023 Jan 24;29(5):e202300069. doi: 10.1002/chem.202300069. Chemistry. 2023. PMID: 36692211
Maytansinol Functionalization: Towards Useful Probes for Studying Microtubule Dynamics.
Boiarska Z, Pérez-Peña H, Abel AC, Marzullo P, Álvarez-Bernad B, Bonato F, Santini B, Horvath D, Lucena-Agell D, Vasile F, Sironi M, Díaz JF, Prota AE, Pieraccini S, Passarella D. Boiarska Z, et al. Among authors: diaz jf. Chemistry. 2023 Jan 24;29(5):e202203431. doi: 10.1002/chem.202203431. Epub 2022 Dec 30. Chemistry. 2023. PMID: 36468686 Free article.
Chemical modulation of microtubule structure through the laulimalide/peloruside site.
Estévez-Gallego J, Álvarez-Bernad B, Pera B, Wullschleger C, Raes O, Menche D, Martínez JC, Lucena-Agell D, Prota AE, Bonato F, Bargsten K, Cornelus J, Giménez-Abián JF, Northcote P, Steinmetz MO, Kamimura S, Altmann KH, Paterson I, Gago F, Van der Eycken J, Díaz JF, Oliva MÁ. Estévez-Gallego J, et al. Among authors: diaz jf. Structure. 2023 Jan 5;31(1):88-99.e5. doi: 10.1016/j.str.2022.11.006. Epub 2022 Dec 2. Structure. 2023. PMID: 36462501 Free article.
119 results