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2020 2
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Force-tuned avidity of spike variant-ACE2 interactions viewed on the single-molecule level.
Zhu R, Canena D, Sikora M, Klausberger M, Seferovic H, Mehdipour AR, Hain L, Laurent E, Monteil V, Wirnsberger G, Wieneke R, Tampé R, Kienzl NF, Mach L, Mirazimi A, Oh YJ, Penninger JM, Hummer G, Hinterdorfer P. Zhu R, et al. Nat Commun. 2022 Dec 24;13(1):7926. doi: 10.1038/s41467-022-35641-3. Nat Commun. 2022. PMID: 36566234 Free PMC article.
Computational epitope map of SARS-CoV-2 spike protein.
Sikora M, von Bülow S, Blanc FEC, Gecht M, Covino R, Hummer G. Sikora M, et al. PLoS Comput Biol. 2021 Apr 1;17(4):e1008790. doi: 10.1371/journal.pcbi.1008790. eCollection 2021 Apr. PLoS Comput Biol. 2021. PMID: 33793546 Free PMC article.
In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges.
Turoňová B, Sikora M, Schürmann C, Hagen WJH, Welsch S, Blanc FEC, von Bülow S, Gecht M, Bagola K, Hörner C, van Zandbergen G, Landry J, de Azevedo NTD, Mosalaganti S, Schwarz A, Covino R, Mühlebach MD, Hummer G, Krijnse Locker J, Beck M. Turoňová B, et al. Science. 2020 Oct 9;370(6513):203-208. doi: 10.1126/science.abd5223. Epub 2020 Aug 18. Science. 2020. PMID: 32817270 Free PMC article.