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Atypical muscarinic allosteric modulation: cooperativity between modulators and their atypical binding topology in muscarinic M2 and M2/M5 chimeric receptors.
Mol Pharmacol. 2005 Dec;68(6):1597-610. doi: 10.1124/mol.105.017707. Epub 2005 Sep 12.
Mol Pharmacol. 2005.
PMID: 16157694
Allosteric site on muscarinic acetylcholine receptors: identification of two amino acids in the muscarinic M2 receptor that account entirely for the M2/M5 subtype selectivities of some structurally diverse allosteric ligands in N-methylscopolamine-occupied receptors.
Voigtländer U, Jöhren K, Mohr M, Raasch A, Tränkle C, Buller S, Ellis J, Höltje HD, Mohr K.
Voigtländer U, et al. Among authors: johren k.
Mol Pharmacol. 2003 Jul;64(1):21-31. doi: 10.1124/mol.64.1.21.
Mol Pharmacol. 2003.
PMID: 12815157
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A model of the human M2 muscarinic acetylcholine receptor.
Jöhren K, Höltje HD.
Jöhren K, et al.
J Comput Aided Mol Des. 2002 Nov;16(11):795-801. doi: 10.1023/a:1023880611709.
J Comput Aided Mol Des. 2002.
PMID: 12825791
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Different environments for a realistic simulation of GPCRs-application to the M2 muscarinic receptor.
Jöhren K, Höltje HD.
Jöhren K, et al.
Arch Pharm (Weinheim). 2005 Jun;338(5-6):260-7. doi: 10.1002/ardp.200400992.
Arch Pharm (Weinheim). 2005.
PMID: 15924369
Review.
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