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AAV2-VEGF-B gene therapy failed to induce angiogenesis in ischemic porcine myocardium due to inflammatory responses.
Korpela H, Lampela J, Airaksinen J, Järveläinen N, Siimes S, Valli K, Nieminen T, Turunen M, Grönman M, Saraste A, Knuuti J, Hakulinen M, Poutiainen P, Kärjä V, Nurro J, Ylä-Herttuala S. Korpela H, et al. Among authors: jarvelainen n. Gene Ther. 2022 Nov;29(10-11):643-652. doi: 10.1038/s41434-022-00322-9. Epub 2022 Feb 7. Gene Ther. 2022. PMID: 35132204 Free PMC article.
Endocardial Gene Delivery Using NOGA Catheter System.
Siimes S, Järveläinen N, Korpela H, Ylä-Herttuala S. Siimes S, et al. Among authors: jarvelainen n. Methods Mol Biol. 2022;2573:179-187. doi: 10.1007/978-1-0716-2707-5_14. Methods Mol Biol. 2022. PMID: 36040595
Gene therapy for ischaemic heart disease and heart failure.
Korpela H, Järveläinen N, Siimes S, Lampela J, Airaksinen J, Valli K, Turunen M, Pajula J, Nurro J, Ylä-Herttuala S. Korpela H, et al. Among authors: jarvelainen n. J Intern Med. 2021 Sep;290(3):567-582. doi: 10.1111/joim.13308. Epub 2021 May 25. J Intern Med. 2021. PMID: 34033164 Free article. Review.
BMP2 gene transfer induces pericardial effusion and inflammatory response in the ischemic porcine myocardium.
Pulkkinen HH, Kivistö-Rahnasto A, Korpela H, Heikkilä M, Järveläinen N, Siimes S, Kilpeläinen L, Laham-Karam N, Ylä-Herttuala S, Laakkonen JP. Pulkkinen HH, et al. Among authors: jarvelainen n. Front Cardiovasc Med. 2023 Nov 3;10:1279613. doi: 10.3389/fcvm.2023.1279613. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 38028463 Free PMC article.