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Gut microbiota regulate hepatic von Willebrand factor synthesis and arterial thrombus formation via Toll-like receptor-2.
Jäckel S, Kiouptsi K, Lillich M, Hendrikx T, Khandagale A, Kollar B, Hörmann N, Reiss C, Subramaniam S, Wilms E, Ebner K, Brühl MV, Rausch P, Baines JF, Haberichter S, Lämmle B, Binder CJ, Jurk K, Ruggeri ZM, Massberg S, Walter U, Ruf W, Reinhardt C. Jäckel S, et al. Blood. 2017 Jul 27;130(4):542-553. doi: 10.1182/blood-2016-11-754416. Epub 2017 Jun 1. Blood. 2017. PMID: 28572286 Free article.
Mice deficient in the anti-haemophilic coagulation factor VIII show increased von Willebrand factor plasma levels.
Kiouptsi K, Grill A, Mann A, Döhrmann M, Lillich M, Jäckel S, Malinarich F, Formes H, Manukyan D, Subramaniam S, Khandagale A, Karwot C, Thal SC, Bosmann M, Scharrer I, Jurk K, Reinhardt C. Kiouptsi K, et al. Among authors: jackel s. PLoS One. 2017 Aug 24;12(8):e0183590. doi: 10.1371/journal.pone.0183590. eCollection 2017. PLoS One. 2017. PMID: 28837614 Free PMC article.
Gut Microbiota Promote Angiotensin II-Induced Arterial Hypertension and Vascular Dysfunction.
Karbach SH, Schönfelder T, Brandão I, Wilms E, Hörmann N, Jäckel S, Schüler R, Finger S, Knorr M, Lagrange J, Brandt M, Waisman A, Kossmann S, Schäfer K, Münzel T, Reinhardt C, Wenzel P. Karbach SH, et al. Among authors: jackel s. J Am Heart Assoc. 2016 Aug 30;5(9):e003698. doi: 10.1161/JAHA.116.003698. J Am Heart Assoc. 2016. PMID: 27577581 Free PMC article.
Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension.
Kossmann S, Lagrange J, Jäckel S, Jurk K, Ehlken M, Schönfelder T, Weihert Y, Knorr M, Brandt M, Xia N, Li H, Daiber A, Oelze M, Reinhardt C, Lackner K, Gruber A, Monia B, Karbach SH, Walter U, Ruggeri ZM, Renné T, Ruf W, Münzel T, Wenzel P. Kossmann S, et al. Among authors: jackel s. Sci Transl Med. 2017 Feb 1;9(375):eaah4923. doi: 10.1126/scitranslmed.aah4923. Sci Transl Med. 2017. PMID: 28148841
The Microbiota Promotes Arterial Thrombosis in Low-Density Lipoprotein Receptor-Deficient Mice.
Kiouptsi K, Jäckel S, Pontarollo G, Grill A, Kuijpers MJE, Wilms E, Weber C, Sommer F, Nagy M, Neideck C, Jansen Y, Ascher S, Formes H, Karwot C, Bayer F, Kollar B, Subramaniam S, Molitor M, Wenzel P, Rosenstiel P, Todorov H, Gerber S, Walter U, Jurk K, Heemskerk JWM, van der Vorst EPC, Döring Y, Reinhardt C. Kiouptsi K, et al. Among authors: jackel s. mBio. 2019 Oct 22;10(5):e02298-19. doi: 10.1128/mBio.02298-19. mBio. 2019. PMID: 31641089 Free PMC article.
Germ-free housing conditions do not affect aortic root and aortic arch lesion size of late atherosclerotic low-density lipoprotein receptor-deficient mice.
Kiouptsi K, Pontarollo G, Todorov H, Braun J, Jäckel S, Koeck T, Bayer F, Karwot C, Karpi A, Gerber S, Jansen Y, Wild P, Ruf W, Daiber A, Van Der Vorst E, Weber C, Döring Y, Reinhardt C. Kiouptsi K, et al. Among authors: jackel s. Gut Microbes. 2020 Nov 1;11(6):1809-1823. doi: 10.1080/19490976.2020.1767463. Epub 2020 Jun 24. Gut Microbes. 2020. PMID: 32579470 Free PMC article.
73 results