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Glucose-dependent insulinotropic polypeptide is required for moderate high-fat diet- but not high-carbohydrate diet-induced weight gain.
Maekawa R, Ogata H, Murase M, Harada N, Suzuki K, Joo E, Sankoda A, Iida A, Izumoto T, Tsunekawa S, Hamada Y, Oiso Y, Inagaki N, Arima H, Hayashi Y, Seino Y. Maekawa R, et al. Among authors: izumoto t. Am J Physiol Endocrinol Metab. 2018 Jun 1;314(6):E572-E583. doi: 10.1152/ajpendo.00352.2017. Epub 2018 Feb 6. Am J Physiol Endocrinol Metab. 2018. PMID: 29406782 Free article.
KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state.
Ogata H, Seino Y, Harada N, Iida A, Suzuki K, Izumoto T, Ishikawa K, Uenishi E, Ozaki N, Hayashi Y, Miki T, Inagaki N, Tsunekawa S, Hamada Y, Seino S, Oiso Y. Ogata H, et al. Among authors: izumoto t. J Endocrinol. 2014 Aug;222(2):191-200. doi: 10.1530/JOE-14-0161. Epub 2014 Jun 2. J Endocrinol. 2014. PMID: 24891433
Long-term pancreatic beta cell exposure to high levels of glucose but not palmitate induces DNA methylation within the insulin gene promoter and represses transcriptional activity.
Ishikawa K, Tsunekawa S, Ikeniwa M, Izumoto T, Iida A, Ogata H, Uenishi E, Seino Y, Ozaki N, Sugimura Y, Hamada Y, Kuroda A, Shinjo K, Kondo Y, Oiso Y. Ishikawa K, et al. Among authors: izumoto t. PLoS One. 2015 Feb 6;10(2):e0115350. doi: 10.1371/journal.pone.0115350. eCollection 2015. PLoS One. 2015. PMID: 25658116 Free PMC article.
Effect of hyperglycemia on hepatocellular carcinoma development in diabetes.
Niwa Y, Ishikawa K, Ishigami M, Honda T, Achiwa K, Izumoto T, Maekawa R, Hosokawa K, Iida A, Seino Y, Hamada Y, Goto H, Oiso Y, Arima H, Tsunekawa S. Niwa Y, et al. Among authors: izumoto t. Biochem Biophys Res Commun. 2015 Jul 31;463(3):344-50. doi: 10.1016/j.bbrc.2015.05.066. Epub 2015 May 28. Biochem Biophys Res Commun. 2015. PMID: 26022129 Free article.
Fructose induces glucose-dependent insulinotropic polypeptide, glucagon-like peptide-1 and insulin secretion: Role of adenosine triphosphate-sensitive K(+) channels.
Seino Y, Ogata H, Maekawa R, Izumoto T, Iida A, Harada N, Miki T, Seino S, Inagaki N, Tsunekawa S, Oiso Y, Hamada Y. Seino Y, et al. Among authors: izumoto t. J Diabetes Investig. 2015 Sep;6(5):522-6. doi: 10.1111/jdi.12356. Epub 2015 May 3. J Diabetes Investig. 2015. PMID: 26417408 Free PMC article.
Endogenous GIP ameliorates impairment of insulin secretion in proglucagon-deficient mice under moderate beta cell damage induced by streptozotocin.
Iida A, Seino Y, Fukami A, Maekawa R, Yabe D, Shimizu S, Kinoshita K, Takagi Y, Izumoto T, Ogata H, Ishikawa K, Ozaki N, Tsunekawa S, Hamada Y, Oiso Y, Arima H, Hayashi Y. Iida A, et al. Among authors: izumoto t. Diabetologia. 2016 Jul;59(7):1533-1541. doi: 10.1007/s00125-016-3935-2. Epub 2016 Apr 6. Diabetologia. 2016. PMID: 27053237 Free PMC article.
TDP-43 regulates early-phase insulin secretion via CaV1.2-mediated exocytosis in islets.
Araki K, Araki A, Honda D, Izumoto T, Hashizume A, Hijikata Y, Yamada S, Iguchi Y, Hara A, Ikumi K, Kawai K, Ishigaki S, Nakamichi Y, Tsunekawa S, Seino Y, Yamamoto A, Takayama Y, Hidaka S, Tominaga M, Ohara-Imaizumi M, Suzuki A, Ishiguro H, Enomoto A, Yoshida M, Arima H, Muramatsu SI, Sobue G, Katsuno M. Araki K, et al. Among authors: izumoto t. J Clin Invest. 2019 Jul 29;129(9):3578-3593. doi: 10.1172/JCI124481. eCollection 2019 Jul 29. J Clin Invest. 2019. PMID: 31355778 Free PMC article.
A novel mechanism of idiopathic orthostatic hypotension and hypocatecholaminemia due to autoimmunity against aromatic l-Amino acid decarboxylase.
Uenishi E, Seino Y, Nakashima A, Kato K, Kato M, Nagasaki H, Ishikawa K, Izumoto T, Yamamoto M, Takahashi Y, Sugimura Y, Oiso Y, Tsunekawa S. Uenishi E, et al. Among authors: izumoto t. Biochem Biophys Res Commun. 2024 Jun 25;714:149940. doi: 10.1016/j.bbrc.2024.149940. Epub 2024 Apr 16. Biochem Biophys Res Commun. 2024. PMID: 38677008
17 results