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The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of BRAF-mutant melanoma cells in combination with other signaling pathway inhibitors.
Langdon CG, Held MA, Platt JT, Meeth K, Iyidogan P, Mamillapalli R, Koo AB, Klein M, Liu Z, Bosenberg MW, Stern DF. Langdon CG, et al. Among authors: iyidogan p. Pigment Cell Melanoma Res. 2015 Jul;28(4):417-30. doi: 10.1111/pcmr.12376. Epub 2015 May 6. Pigment Cell Melanoma Res. 2015. PMID: 25854919 Free PMC article.
Combinatorial Screening of Pancreatic Adenocarcinoma Reveals Sensitivity to Drug Combinations Including Bromodomain Inhibitor Plus Neddylation Inhibitor.
Langdon CG, Platt JT, Means RE, Iyidogan P, Mamillapalli R, Klein M, Held MA, Lee JW, Koo JS, Hatzis C, Hochster HS, Stern DF. Langdon CG, et al. Among authors: iyidogan p. Mol Cancer Ther. 2017 Jun;16(6):1041-1053. doi: 10.1158/1535-7163.MCT-16-0794. Epub 2017 Mar 14. Mol Cancer Ther. 2017. PMID: 28292938 Free PMC article.
A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium.
Mukerjee A, Iyidogan P, Castellanos-Gonzalez A, Cisneros JA, Czyzyk D, Ranjan AP, Jorgensen WL, White AC Jr, Vishwanatha JK, Anderson KS. Mukerjee A, et al. Among authors: iyidogan p. Bioorg Med Chem Lett. 2015;25(10):2065-7. doi: 10.1016/j.bmcl.2015.03.091. Epub 2015 Apr 4. Bioorg Med Chem Lett. 2015. PMID: 25900220 Free PMC article.
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