Iyer D - Search Results

1

Smad3 regulates smooth muscle cell fate and mediates adverse remodeling and calcification of the atherosclerotic plaque.

Cheng P, Wirka RC, Kim JB, Kim HJ, Nguyen T, Kundu R, Zhao Q, Sharma D, Pedroza A, Nagao M, Iyer D, Fischbein MP, Quertermous T. Cheng P, et al. Among authors: iyer d. Nat Cardiovasc Res. 2022 Apr;1(4):322-333. doi: 10.1038/s44161-022-00042-8. Epub 2022 Apr 13. Nat Cardiovasc Res. 2022. PMID: 36246779 Free PMC article.

2

Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk.

Iyer D, Zhao Q, Wirka R, Naravane A, Nguyen T, Liu B, Nagao M, Cheng P, Miller CL, Kim JB, Pjanic M, Quertermous T. Iyer D, et al. PLoS Genet. 2018 Oct 11;14(10):e1007681. doi: 10.1371/journal.pgen.1007681. eCollection 2018 Oct. PLoS Genet. 2018. PMID: 30307970 Free PMC article.

3

Molecular mechanisms of coronary disease revealed using quantitative trait loci for TCF21 binding, chromatin accessibility, and chromosomal looping.

Zhao Q, Dacre M, Nguyen T, Pjanic M, Liu B, Iyer D, Cheng P, Wirka R, Kim JB, Fraser HB, Quertermous T. Zhao Q, et al. Among authors: iyer d. Genome Biol. 2020 Jun 8;21(1):135. doi: 10.1186/s13059-020-02049-5. Genome Biol. 2020. PMID: 32513244 Free PMC article.

4

TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells.

Kim JB, Pjanic M, Nguyen T, Miller CL, Iyer D, Liu B, Wang T, Sazonova O, Carcamo-Orive I, Matic LP, Maegdefessel L, Hedin U, Quertermous T. Kim JB, et al. Among authors: iyer d. PLoS Genet. 2017 May 8;13(5):e1006750. doi: 10.1371/journal.pgen.1006750. eCollection 2017 May. PLoS Genet. 2017. PMID: 28481916 Free PMC article.

5

Embryological Origin of Human Smooth Muscle Cells Influences Their Ability to Support Endothelial Network Formation.

Bargehr J, Low L, Cheung C, Bernard WG, Iyer D, Bennett MR, Gambardella L, Sinha S. Bargehr J, et al. Among authors: iyer d. Stem Cells Transl Med. 2016 Jul;5(7):946-59. doi: 10.5966/sctm.2015-0282. Epub 2016 May 18. Stem Cells Transl Med. 2016. PMID: 27194743 Free PMC article.

6

Embryonic origins of human vascular smooth muscle cells: implications for in vitro modeling and clinical application.

Sinha S, Iyer D, Granata A. Sinha S, et al. Among authors: iyer d. Cell Mol Life Sci. 2014 Jun;71(12):2271-88. doi: 10.1007/s00018-013-1554-3. Epub 2014 Jan 18. Cell Mol Life Sci. 2014. PMID: 24442477 Free PMC article. Review.

7

Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells.

Iyer D, Gambardella L, Bernard WG, Serrano F, Mascetti VL, Pedersen RA, Talasila A, Sinha S. Iyer D, et al. Development. 2015 Apr 15;142(8):1528-41. doi: 10.1242/dev.119271. Epub 2015 Mar 26. Development. 2015. PMID: 25813541 Free PMC article.

8

A Novel Human Pluripotent Stem Cell-Derived Neural Crest Model of Treacher Collins Syndrome Shows Defects in Cell Death and Migration.

Serrano F, Bernard WG, Granata A, Iyer D, Steventon B, Kim M, Vallier L, Gambardella L, Sinha S. Serrano F, et al. Among authors: iyer d. Stem Cells Dev. 2019 Jan 15;28(2):81-100. doi: 10.1089/scd.2017.0234. Epub 2018 Dec 18. Stem Cells Dev. 2019. PMID: 30375284 Free PMC article.

9

Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs.

Bertero A, Pawlowski M, Ortmann D, Snijders K, Yiangou L, Cardoso de Brito M, Brown S, Bernard WG, Cooper JD, Giacomelli E, Gambardella L, Hannan NR, Iyer D, Sampaziotis F, Serrano F, Zonneveld MC, Sinha S, Kotter M, Vallier L. Bertero A, et al. Among authors: iyer d. Development. 2016 Dec 1;143(23):4405-4418. doi: 10.1242/dev.138081. Development. 2016. PMID: 27899508 Free PMC article.

10

Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells.

Iyer D, Gambardella L, Bernard WG, Serrano F, Mascetti VL, Pedersen RA, Sinha S, Talasila A. Iyer D, et al. Development. 2016 Mar 1;143(5):904. doi: 10.1242/dev.136143. Development. 2016. PMID: 26932673 Free PMC article. No abstract available.

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