Iyer A - Search Results

1

Discovery of a new flavin N5-adduct in a tyrosine to phenylalanine variant of d-Arginine dehydrogenase.

Iyer A, Reis RAG, Agniswamy J, Weber IT, Gadda G. Iyer A, et al. Arch Biochem Biophys. 2022 Jan 15;715:109100. doi: 10.1016/j.abb.2021.109100. Epub 2021 Dec 2. Arch Biochem Biophys. 2022. PMID: 34864048

2

Amine oxidation by d-arginine dehydrogenase in Pseudomonas aeruginosa.

Ouedraogo D, Ball J, Iyer A, Reis RAG, Vodovoz M, Gadda G. Ouedraogo D, et al. Among authors: iyer a. Arch Biochem Biophys. 2017 Oct 15;632:192-201. doi: 10.1016/j.abb.2017.06.013. Epub 2017 Jun 15. Arch Biochem Biophys. 2017. PMID: 28625766 Review.

3

A Single-Point Mutation in d-Arginine Dehydrogenase Unlocks a Transient Conformational State Resulting in Altered Cofactor Reactivity.

Iyer A, Reis RAG, Gannavaram S, Momin M, Spring-Connell AM, Orozco-Gonzalez Y, Agniswamy J, Hamelberg D, Weber IT, Gozem S, Wang S, Germann MW, Gadda G. Iyer A, et al. Biochemistry. 2021 Mar 9;60(9):711-724. doi: 10.1021/acs.biochem.1c00054. Epub 2021 Feb 25. Biochemistry. 2021. PMID: 33630571

4

A new mitochondrial pool of cyclin E, regulated by Drp1, is linked to cell-density-dependent cell proliferation.

Parker DJ, Iyer A, Shah S, Moran A, Hjelmeland AB, Basu MK, Liu R, Mitra K. Parker DJ, et al. Among authors: iyer a. J Cell Sci. 2015 Nov 15;128(22):4171-82. doi: 10.1242/jcs.172429. Epub 2015 Oct 7. J Cell Sci. 2015. PMID: 26446260 Free PMC article.

5

Identification of causal genetic drivers of human disease through systems-level analysis of regulatory networks.

Chen JC, Alvarez MJ, Talos F, Dhruv H, Rieckhof GE, Iyer A, Diefes KL, Aldape K, Berens M, Shen MM, Califano A. Chen JC, et al. Among authors: iyer a. Cell. 2014 Oct 9;159(2):402-14. doi: 10.1016/j.cell.2014.09.021. Cell. 2014. PMID: 25303533 Free PMC article.

6

Elucidating Compound Mechanism of Action by Network Perturbation Analysis.

Woo JH, Shimoni Y, Yang WS, Subramaniam P, Iyer A, Nicoletti P, Rodríguez Martínez M, López G, Mattioli M, Realubit R, Karan C, Stockwell BR, Bansal M, Califano A. Woo JH, et al. Among authors: iyer a. Cell. 2015 Jul 16;162(2):441-451. doi: 10.1016/j.cell.2015.05.056. Cell. 2015. PMID: 26186195 Free PMC article.

7

An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma.

Sumazin P, Yang X, Chiu HS, Chung WJ, Iyer A, Llobet-Navas D, Rajbhandari P, Bansal M, Guarnieri P, Silva J, Califano A. Sumazin P, et al. Among authors: iyer a. Cell. 2011 Oct 14;147(2):370-81. doi: 10.1016/j.cell.2011.09.041. Cell. 2011. PMID: 22000015 Free PMC article.

8

Structural requirements for the inhibition of calcium mobilization and mast cell activation by the pyrazole derivative BTP2.

Law M, Morales JL, Mottram LF, Iyer A, Peterson BR, August A. Law M, et al. Among authors: iyer a. Int J Biochem Cell Biol. 2011 Aug;43(8):1228-39. doi: 10.1016/j.biocel.2011.04.016. Epub 2011 May 4. Int J Biochem Cell Biol. 2011. PMID: 21558014 Free PMC article.

9

Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks.

Chiu HS, Llobet-Navas D, Yang X, Chung WJ, Ambesi-Impiombato A, Iyer A, Kim HR, Seviour EG, Luo Z, Sehgal V, Moss T, Lu Y, Ram P, Silva J, Mills GB, Califano A, Sumazin P. Chiu HS, et al. Among authors: iyer a. Genome Res. 2015 Feb;25(2):257-67. doi: 10.1101/gr.178194.114. Epub 2014 Nov 5. Genome Res. 2015. PMID: 25378249 Free PMC article.

10

Cross-Cohort Analysis Identifies a TEAD4-MYCN Positive Feedback Loop as the Core Regulatory Element of High-Risk Neuroblastoma.

Rajbhandari P, Lopez G, Capdevila C, Salvatori B, Yu J, Rodriguez-Barrueco R, Martinez D, Yarmarkovich M, Weichert-Leahey N, Abraham BJ, Alvarez MJ, Iyer A, Harenza JL, Oldridge D, De Preter K, Koster J, Asgharzadeh S, Seeger RC, Wei JS, Khan J, Vandesompele J, Mestdagh P, Versteeg R, Look AT, Young RA, Iavarone A, Lasorella A, Silva JM, Maris JM, Califano A. Rajbhandari P, et al. Among authors: iyer a. Cancer Discov. 2018 May;8(5):582-599. doi: 10.1158/2159-8290.CD-16-0861. Epub 2018 Mar 6. Cancer Discov. 2018. PMID: 29510988 Free PMC article.

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