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Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies.
Saei A, Palafox M, Benoukraf T, Kumari N, Jaynes PW, Iyengar PV, Muñoz-Couselo E, Nuciforo P, Cortés J, Nötzel C, Kumarakulasinghe NB, Richard JLC, Bin Adam Isa ZF, Pang B, Guzman M, Siqin Z, Yang H, Tam WL, Serra V, Eichhorn PJA. Saei A, et al. Among authors: iyengar pv. J Exp Med. 2018 Jul 2;215(7):1913-1928. doi: 10.1084/jem.20171960. Epub 2018 Jun 7. J Exp Med. 2018. PMID: 29880484 Free PMC article.
The roles of ubiquitin modifying enzymes in neoplastic disease.
Kumari N, Jaynes PW, Saei A, Iyengar PV, Richard JLC, Eichhorn PJA. Kumari N, et al. Among authors: iyengar pv. Biochim Biophys Acta Rev Cancer. 2017 Dec;1868(2):456-483. doi: 10.1016/j.bbcan.2017.09.002. Epub 2017 Sep 18. Biochim Biophys Acta Rev Cancer. 2017. PMID: 28923280 Review.
c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression.
Sim WJ, Iyengar PV, Lama D, Lui SKL, Ng HC, Haviv-Shapira L, Domany E, Kappei D, Tan TZ, Saei A, Jaynes PW, Verma CS, Kumar AP, Rouanne M, Ha HK, Radulescu C, Ten Dijke P, Eichhorn PJA, Thiery JP. Sim WJ, et al. Among authors: iyengar pv. Nat Commun. 2019 Sep 25;10(1):4349. doi: 10.1038/s41467-019-12241-2. Nat Commun. 2019. PMID: 31554791 Free PMC article.
Author Correction: c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression.
Sim WJ, Iyengar PV, Lama D, Lui SKL, Ng HC, Haviv-Shapira L, Domany E, Kappei D, Tan TZ, Saei A, Jaynes PW, Verma CS, Kumar AP, Rouanne M, Ha HK, Radulescu C, Ten Dijke P, Eichhorn PJA, Thiery JP. Sim WJ, et al. Among authors: iyengar pv. Nat Commun. 2019 Nov 8;10(1):5148. doi: 10.1038/s41467-019-13095-4. Nat Commun. 2019. PMID: 31704935 Free PMC article.
USP26 regulates TGF-β signaling by deubiquitinating and stabilizing SMAD7.
Kit Leng Lui S, Iyengar PV, Jaynes P, Isa ZFBA, Pang B, Tan TZ, Eichhorn PJA. Kit Leng Lui S, et al. Among authors: iyengar pv. EMBO Rep. 2020 Jan 7;21(1):e49618. doi: 10.15252/embr.201949618. Epub 2019 Dec 20. EMBO Rep. 2020. PMID: 31910334 Free PMC article. No abstract available.
TRAF4 Inhibits Bladder Cancer Progression by Promoting BMP/SMAD Signaling.
Iyengar PV, Marvin DL, Lama D, Tan TZ, Suriyamurthy S, Xie F, van Dinther M, Mei H, Verma CS, Zhang L, Ritsma L, Ten Dijke P. Iyengar PV, et al. Mol Cancer Res. 2022 Oct 4;20(10):1516-1531. doi: 10.1158/1541-7786.MCR-20-1029. Mol Cancer Res. 2022. PMID: 35731212 Free PMC article.
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