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Actin-binding protein filamin-A drives tau aggregation and contributes to progressive supranuclear palsy pathology.
Tsujikawa K, Hamanaka K, Riku Y, Hattori Y, Hara N, Iguchi Y, Ishigaki S, Hashizume A, Miyatake S, Mitsuhashi S, Miyazaki Y, Kataoka M, Jiayi L, Yasui K, Kuru S, Koike H, Kobayashi K, Sahara N, Ozaki N, Yoshida M, Kakita A, Saito Y, Iwasaki Y, Miyashita A, Iwatsubo T; Japanese Alzheimer’s Disease Neuroimaging Initiative (J-ADNI); Ikeuchi T; Japanese Longitudinal Biomarker Study in PSP and CBD (JALPAC) Consortium; Miyata T, Sobue G, Matsumoto N, Sahashi K, Katsuno M. Tsujikawa K, et al. Among authors: iwatsubo t. Sci Adv. 2022 May 27;8(21):eabm5029. doi: 10.1126/sciadv.abm5029. Epub 2022 May 25. Sci Adv. 2022. PMID: 35613261 Free PMC article.
Enhanced accumulation of phosphorylated alpha-synuclein and elevated beta-amyloid 42/40 ratio caused by expression of the presenilin-1 deltaT440 mutant associated with familial Lewy body disease and variant Alzheimer's disease.
Kaneko H, Kakita A, Kasuga K, Nozaki H, Ishikawa A, Miyashita A, Kuwano R, Ito G, Iwatsubo T, Takahashi H, Nishizawa M, Onodera O, Sisodia SS, Ikeuchi T. Kaneko H, et al. Among authors: iwatsubo t. J Neurosci. 2007 Nov 28;27(48):13092-7. doi: 10.1523/JNEUROSCI.4244-07.2007. J Neurosci. 2007. PMID: 18045903 Free PMC article.
Lewy body pathology involves cutaneous nerves.
Ikemura M, Saito Y, Sengoku R, Sakiyama Y, Hatsuta H, Kanemaru K, Sawabe M, Arai T, Ito G, Iwatsubo T, Fukayama M, Murayama S. Ikemura M, et al. Among authors: iwatsubo t. J Neuropathol Exp Neurol. 2008 Oct;67(10):945-53. doi: 10.1097/NEN.0b013e318186de48. J Neuropathol Exp Neurol. 2008. PMID: 18800013
Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau.
Taniguchi-Watanabe S, Arai T, Kametani F, Nonaka T, Masuda-Suzukake M, Tarutani A, Murayama S, Saito Y, Arima K, Yoshida M, Akiyama H, Robinson A, Mann DMA, Iwatsubo T, Hasegawa M. Taniguchi-Watanabe S, et al. Among authors: iwatsubo t. Acta Neuropathol. 2016 Feb;131(2):267-280. doi: 10.1007/s00401-015-1503-3. Epub 2015 Nov 4. Acta Neuropathol. 2016. PMID: 26538150 Free PMC article.
Clinical and cognitive characteristics of preclinical Alzheimer's disease in the Japanese Alzheimer's Disease Neuroimaging Initiative cohort.
Ihara R, Iwata A, Suzuki K, Ikeuchi T, Kuwano R, Iwatsubo T; Japanese Alzheimer's Disease Neuroimaging Initiative. Ihara R, et al. Among authors: iwatsubo t. Alzheimers Dement (N Y). 2018 Nov 26;4:645-651. doi: 10.1016/j.trci.2018.10.004. eCollection 2018. Alzheimers Dement (N Y). 2018. PMID: 30511010 Free PMC article.
Lower Serum Calcium as a Potentially Associated Factor for Conversion of Mild Cognitive Impairment to Early Alzheimer's Disease in the Japanese Alzheimer's Disease Neuroimaging Initiative.
Sato K, Mano T, Ihara R, Suzuki K, Tomita N, Arai H, Ishii K, Senda M, Ito K, Ikeuchi T, Kuwano R, Matsuda H, Iwatsubo T, Toda T, Iwata A; Alzheimer’s Disease Neuroimaging Initiative, and Japanese Alzheimer’s Disease Neuroimaging Initiative. Sato K, et al. Among authors: iwatsubo t. J Alzheimers Dis. 2019;68(2):777-788. doi: 10.3233/JAD-181115. J Alzheimers Dis. 2019. PMID: 30814351
[Recommendations (Proposal) for promoting research for overcoming neurological diseases 2020].
Mochizuki H, Aoki M, Ikenaka K, Inoue H, Iwatsubo T, Ugawa Y, Okazawa H, Ono K, Onodera O, Kitagawa K, Saito Y, Shimohata T, Takahashi R, Toda T, Nakahara J, Matsumoto R, Mizusawa H, Mitsui J, Murayama S, Katsuno M; Future Vision Committee of Japanese Society of Neurology; Aoki Y, Ishiura H, Izumi Y, Koike H, Shimada H, Takahashi Y, Tokuda T, Nakajima H, Hatano T, Misawa S, Watanabe H. Mochizuki H, et al. Among authors: iwatsubo t. Rinsho Shinkeigaku. 2021 Nov 24;61(11):709-721. doi: 10.5692/clinicalneurol.cn-001639. Epub 2021 Oct 16. Rinsho Shinkeigaku. 2021. PMID: 34657923 Japanese.
[Recommendations (Proposal) for promoting research for overcoming neurological diseases 2020].
Mochizuki H, Aoki M, Ikenaka K, Inoue H, Iwatsubo T, Ugawa Y, Okazawa H, Ono K, Onodera O, Kitagawa K, Saito Y, Shimohata T, Takahashi R, Toda T, Nakahara J, Matsumoto R, Mizusawa H, Mitsui J, Murayama S, Katsuno M; Future Vision Committee of Japanese Society of Neurology; Aoki Y, Ishiura H, Izumi Y, Koike H, Shimada H, Takahashi Y, Tokuda T, Nakajima H, Hatano T, Misawa S, Watanabe H. Mochizuki H, et al. Among authors: iwatsubo t. Rinsho Shinkeigaku. 2022 Jun 24;62(6):429-442. doi: 10.5692/clinicalneurol.cn-001695. Epub 2022 May 28. Rinsho Shinkeigaku. 2022. PMID: 35644579 Japanese.
603 results