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Medium-chain triglycerides inhibit long-chain triglyceride-induced GIP secretion through GPR120-dependent inhibition of CCK.
Murata Y, Harada N, Kishino S, Iwasaki K, Ikeguchi-Ogura E, Yamane S, Kato T, Kanemaru Y, Sankoda A, Hatoko T, Kiyobayashi S, Ogawa J, Hirasawa A, Inagaki N. Murata Y, et al. Among authors: iwasaki k. iScience. 2021 Aug 9;24(9):102963. doi: 10.1016/j.isci.2021.102963. eCollection 2021 Sep 24. iScience. 2021. PMID: 34466786 Free PMC article.
Free fatty acid receptor GPR120 is highly expressed in enteroendocrine K cells of the upper small intestine and has a critical role in GIP secretion after fat ingestion.
Iwasaki K, Harada N, Sasaki K, Yamane S, Iida K, Suzuki K, Hamasaki A, Nasteska D, Shibue K, Joo E, Harada T, Hashimoto T, Asakawa Y, Hirasawa A, Inagaki N. Iwasaki K, et al. Endocrinology. 2015 Mar;156(3):837-46. doi: 10.1210/en.2014-1653. Epub 2014 Dec 23. Endocrinology. 2015. PMID: 25535828
Fatty acid-binding protein 5 regulates diet-induced obesity via GIP secretion from enteroendocrine K cells in response to fat ingestion.
Shibue K, Yamane S, Harada N, Hamasaki A, Suzuki K, Joo E, Iwasaki K, Nasteska D, Harada T, Hayashi Y, Adachi Y, Owada Y, Takayanagi R, Inagaki N. Shibue K, et al. Among authors: iwasaki k. Am J Physiol Endocrinol Metab. 2015 Apr 1;308(7):E583-91. doi: 10.1152/ajpendo.00543.2014. Epub 2015 Jan 27. Am J Physiol Endocrinol Metab. 2015. PMID: 25628425 Free article.
Nardilysin Is Required for Maintaining Pancreatic β-Cell Function.
Nishi K, Sato Y, Ohno M, Hiraoka Y, Saijo S, Sakamoto J, Chen PM, Morita Y, Matsuda S, Iwasaki K, Sugizaki K, Harada N, Mukumoto Y, Kiyonari H, Furuyama K, Kawaguchi Y, Uemoto S, Kita T, Inagaki N, Kimura T, Nishi E. Nishi K, et al. Among authors: iwasaki k. Diabetes. 2016 Oct;65(10):3015-27. doi: 10.2337/db16-0178. Epub 2016 Jul 6. Diabetes. 2016. PMID: 27385158
1,808 results