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Senolytic vaccination improves normal and pathological age-related phenotypes and increases lifespan in progeroid mice.
Suda M, Shimizu I, Katsuumi G, Yoshida Y, Hayashi Y, Ikegami R, Matsumoto N, Yoshida Y, Mikawa R, Katayama A, Wada J, Seki M, Suzuki Y, Iwama A, Nakagami H, Nagasawa A, Morishita R, Sugimoto M, Okuda S, Tsuchida M, Ozaki K, Nakanishi-Matsui M, Minamino T. Suda M, et al. Among authors: iwama a. Nat Aging. 2021 Dec;1(12):1117-1126. doi: 10.1038/s43587-021-00151-2. Epub 2021 Dec 10. Nat Aging. 2021. PMID: 37117524
Obesity accelerates hair thinning by stem cell-centric converging mechanisms.
Morinaga H, Mohri Y, Grachtchouk M, Asakawa K, Matsumura H, Oshima M, Takayama N, Kato T, Nishimori Y, Sorimachi Y, Takubo K, Suganami T, Iwama A, Iwakura Y, Dlugosz AA, Nishimura EK. Morinaga H, et al. Among authors: iwama a. Nature. 2021 Jul;595(7866):266-271. doi: 10.1038/s41586-021-03624-x. Epub 2021 Jun 23. Nature. 2021. PMID: 34163066 Free PMC article.
Unraveling unique features of plasma cell clones in POEMS syndrome with single-cell analysis.
Isshiki Y, Oshima M, Mimura N, Kayamori K, Miyamoto-Nagai Y, Seki M, Nakajima-Takagi Y, Kanamori T, Iwamoto E, Muto T, Tsukamoto S, Takeda Y, Ohwada C, Misawa S, Ikeda JI, Sanada M, Kuwabara S, Suzuki Y, Sakaida E, Nakaseko C, Iwama A. Isshiki Y, et al. Among authors: iwama a. JCI Insight. 2022 Oct 24;7(20):e151482. doi: 10.1172/jci.insight.151482. JCI Insight. 2022. PMID: 36129760 Free PMC article.
Concurrent loss of Ezh2 and Tet2 cooperates in the pathogenesis of myelodysplastic disorders.
Muto T, Sashida G, Oshima M, Wendt GR, Mochizuki-Kashio M, Nagata Y, Sanada M, Miyagi S, Saraya A, Kamio A, Nagae G, Nakaseko C, Yokote K, Shimoda K, Koseki H, Suzuki Y, Sugano S, Aburatani H, Ogawa S, Iwama A. Muto T, et al. Among authors: iwama a. J Exp Med. 2013 Nov 18;210(12):2627-39. doi: 10.1084/jem.20131144. Epub 2013 Nov 11. J Exp Med. 2013. PMID: 24218139 Free PMC article.
Limited rejuvenation of aged hematopoietic stem cells in young bone marrow niche.
Kuribayashi W, Oshima M, Itokawa N, Koide S, Nakajima-Takagi Y, Yamashita M, Yamazaki S, Rahmutulla B, Miura F, Ito T, Kaneda A, Iwama A. Kuribayashi W, et al. Among authors: iwama a. J Exp Med. 2021 Mar 1;218(3):e20192283. doi: 10.1084/jem.20192283. J Exp Med. 2021. PMID: 33231616 Free PMC article.
315 results