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NLRP3 protein deficiency exacerbates hyperoxia-induced lethality through Stat3 protein signaling independent of interleukin-1β.
Mizushina Y, Shirasuna K, Usui F, Karasawa T, Kawashima A, Kimura H, Kobayashi M, Komada T, Inoue Y, Mato N, Yamasawa H, Latz E, Iwakura Y, Kasahara T, Bando M, Sugiyama Y, Takahashi M. Mizushina Y, et al. Among authors: iwakura y. J Biol Chem. 2015 Feb 20;290(8):5065-5077. doi: 10.1074/jbc.M114.603217. Epub 2014 Dec 29. J Biol Chem. 2015. PMID: 25548278 Free PMC article.
AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice.
Hupa KJ, Stein K, Schneider R, Lysson M, Schneiker B, Hornung V, Latz E, Iwakura Y, Kalff JC, Wehner S. Hupa KJ, et al. Among authors: iwakura y. Sci Rep. 2019 Jul 22;9(1):10602. doi: 10.1038/s41598-019-46968-1. Sci Rep. 2019. PMID: 31332247 Free PMC article.
Elevation of pro-inflammatory cytokine levels following anti-resorptive drug treatment is required for osteonecrosis development in infectious osteomyelitis.
Morita M, Iwasaki R, Sato Y, Kobayashi T, Watanabe R, Oike T, Nakamura S, Keneko Y, Miyamoto K, Ishihara K, Iwakura Y, Ishii K, Matsumoto M, Nakamura M, Kawana H, Nakagawa T, Miyamoto T. Morita M, et al. Among authors: iwakura y. Sci Rep. 2017 Apr 7;7:46322. doi: 10.1038/srep46322. Sci Rep. 2017. PMID: 28387378 Free PMC article.
IL-6, IL-17 and Stat3 are required for auto-inflammatory syndrome development in mouse.
Oike T, Kanagawa H, Sato Y, Kobayashi T, Nakatsukasa H, Miyamoto K, Nakamura S, Kaneko Y, Kobayashi S, Harato K, Yoshimura A, Iwakura Y, Takeuchi T, Matsumoto M, Nakamura M, Niki Y, Miyamoto T. Oike T, et al. Among authors: iwakura y. Sci Rep. 2018 Oct 25;8(1):15783. doi: 10.1038/s41598-018-34173-5. Sci Rep. 2018. PMID: 30361689 Free PMC article.
Interleukin 17A: a Janus-faced regulator of osteoporosis.
Scheffler JM, Grahnemo L, Engdahl C, Drevinge C, Gustafsson KL, Corciulo C, Lawenius L, Iwakura Y, Sjögren K, Lagerquist MK, Carlsten H, Ohlsson C, Islander U. Scheffler JM, et al. Among authors: iwakura y. Sci Rep. 2020 Mar 30;10(1):5692. doi: 10.1038/s41598-020-62562-2. Sci Rep. 2020. PMID: 32231224 Free PMC article.
788 results