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Neurolysin knockout mice generation and initial phenotype characterization.
Cavalcanti DM, Castro LM, Rosa Neto JC, Seelaender M, Neves RX, Oliveira V, Forti FL, Iwai LK, Gozzo FC, Todiras M, Schadock I, Barros CC, Bader M, Ferro ES. Cavalcanti DM, et al. Among authors: iwai lk. J Biol Chem. 2014 May 30;289(22):15426-40. doi: 10.1074/jbc.M113.539148. Epub 2014 Apr 9. J Biol Chem. 2014. PMID: 24719317 Free PMC article.
In vitro cleavage of bioactive peptides by peptidases from Bothrops jararaca venom and its neutralization by bothropic antivenom produced by Butantan Institute: Major contribution of serine peptidases.
Kuniyoshi AK, Kodama RT, Moraes LHF, Duzzi B, Iwai LK, Lima IF, Cajado-Carvalho D, Portaro FV. Kuniyoshi AK, et al. Among authors: iwai lk. Toxicon. 2017 Oct;137:114-119. doi: 10.1016/j.toxicon.2017.07.020. Epub 2017 Jul 28. Toxicon. 2017. PMID: 28759785 Free article.
Thimet Oligopeptidase (EC 3.4.24.15) Key Functions Suggested by Knockout Mice Phenotype Characterization.
Santos NBD, Franco RD, Camarini R, Munhoz CD, Eichler RAS, Gewehr MCF, Reckziegel P, Llanos RP, Dale CS, Silva VROD, Borges VF, Lima BHF, Cunha FQ, Visniauskas B, Chagas JR, Tufik S, Peres FF, Abilio VC, Florio JC, Iwai LK, Rioli V, Presoto BC, Guimaraes AO, Pesquero JB, Bader M, Castro LM, Ferro ES. Santos NBD, et al. Among authors: iwai lk. Biomolecules. 2019 Aug 19;9(8):382. doi: 10.3390/biom9080382. Biomolecules. 2019. PMID: 31431000 Free PMC article.
Experimental antivenom against serine proteases from the Bothrops jararaca venom obtained in mice, and its comparison with the antibothropic serum from the Butantan Institute.
Kuniyoshi AK, Kodama RT, Cajado-Carvalho D, Iwai LK, Kitano E, da Silva CCF, Duzzi B, Dias da Silva W, Portaro FC. Kuniyoshi AK, et al. Among authors: iwai lk. Toxicon. 2019 Nov;169:59-67. doi: 10.1016/j.toxicon.2019.09.001. Epub 2019 Sep 5. Toxicon. 2019. PMID: 31494207 Free article.
58 results