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Time to evolve: predicting engineered T cell-associated toxicity with next-generation models.
Donnadieu E, Luu M, Alb M, Anliker B, Arcangeli S, Bonini C, De Angelis B, Choudhary R, Espie D, Galy A, Holland C, Ivics Z, Kantari-Mimoun C, Kersten MJ, Köhl U, Kuhn C, Laugel B, Locatelli F, Marchiq I, Markman J, Moresco MA, Morris E, Negre H, Quintarelli C, Rade M, Reiche K, Renner M, Ruggiero E, Sanges C, Stauss H, Themeli M, Van den Brulle J, Hudecek M, Casucci M. Donnadieu E, et al. Among authors: ivics z. J Immunother Cancer. 2022 May;10(5):e003486. doi: 10.1136/jitc-2021-003486. J Immunother Cancer. 2022. PMID: 35577500 Free PMC article. Review.
Minicircle-Based Engineering of Chimeric Antigen Receptor (CAR) T Cells.
Hudecek M, Gogishvili T, Monjezi R, Wegner J, Shankar R, Kruesemann C, Miskey C, Ivics Z, Schmeer M, Schleef M. Hudecek M, et al. Among authors: ivics z. Recent Results Cancer Res. 2016;209:37-50. doi: 10.1007/978-3-319-42934-2_3. Recent Results Cancer Res. 2016. PMID: 28101686 Review.
A highly soluble Sleeping Beauty transposase improves control of gene insertion.
Querques I, Mades A, Zuliani C, Miskey C, Alb M, Grueso E, Machwirth M, Rausch T, Einsele H, Ivics Z, Hudecek M, Barabas O. Querques I, et al. Among authors: ivics z. Nat Biotechnol. 2019 Dec;37(12):1502-1512. doi: 10.1038/s41587-019-0291-z. Epub 2019 Nov 4. Nat Biotechnol. 2019. PMID: 31685959 Free PMC article.
CARAMBA: a first-in-human clinical trial with SLAMF7 CAR-T cells prepared by virus-free Sleeping Beauty gene transfer to treat multiple myeloma.
Prommersberger S, Reiser M, Beckmann J, Danhof S, Amberger M, Quade-Lyssy P, Einsele H, Hudecek M, Bonig H, Ivics Z. Prommersberger S, et al. Among authors: ivics z. Gene Ther. 2021 Sep;28(9):560-571. doi: 10.1038/s41434-021-00254-w. Epub 2021 Apr 13. Gene Ther. 2021. PMID: 33846552 Free PMC article. Clinical Trial.
205 results