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Recent successes in therapeutics for Ebola virus disease: no time for complacency.
Iversen PL, Kane CD, Zeng X, Panchal RG, Warren TK, Radoshitzky SR, Kuhn JH, Mudhasani RR, Cooper CL, Shurtleff AC, Nasar F, Sunay MM, Duplantier AJ, Eaton BP, Zumbrun EE, Bixler SL, Martin S, Meinig JM, Chiang CY, Sanchez-Lockhart M, Palacios GF, Kugelman JR, Martins KA, Pitt ML, Crozier I, Saunders DL. Iversen PL, et al. Lancet Infect Dis. 2020 Sep;20(9):e231-e237. doi: 10.1016/S1473-3099(20)30282-6. Epub 2020 Jun 18. Lancet Infect Dis. 2020. PMID: 32563280 Free PMC article. Review.
Ebola virus persistence and disease recrudescence in the brains of antibody-treated nonhuman primate survivors.
Liu J, Trefry JC, Babka AM, Schellhase CW, Coffin KM, Williams JA, Raymond JLW, Facemire PR, Chance TB, Davis NM, Scruggs JL, Rossi FD, Haddow AD, Zelko JM, Bixler SL, Crozier I, Iversen PL, Pitt ML, Kuhn JH, Palacios G, Zeng X. Liu J, et al. Among authors: iversen pl. Sci Transl Med. 2022 Feb 9;14(631):eabi5229. doi: 10.1126/scitranslmed.abi5229. Epub 2022 Feb 9. Sci Transl Med. 2022. PMID: 35138912
Remdesivir is efficacious in rhesus monkeys exposed to aerosolized Ebola virus.
Warren TK, Kane CD, Wells J, Stuthman KS, Van Tongeren SA, Garza NL, Donnelly G, Steffens J, Gomba L, Weidner JM, Norris S, Zeng X, Bannister R, Cihlar T, Bavari S, Porter DP, Iversen PL. Warren TK, et al. Among authors: iversen pl. Sci Rep. 2021 Sep 30;11(1):19458. doi: 10.1038/s41598-021-98971-0. Sci Rep. 2021. PMID: 34593911 Free PMC article.
Induced IL-10 splice altering approach to antiviral drug discovery.
Panchal RG, Mourich DV, Bradfute S, Hauck LL, Warfield KL, Iversen PL, Bavari S. Panchal RG, et al. Among authors: iversen pl. Nucleic Acid Ther. 2014 Jun;24(3):179-85. doi: 10.1089/nat.2013.0457. Epub 2014 Mar 21. Nucleic Acid Ther. 2014. PMID: 24655055
Delayed Time-to-Treatment of an Antisense Morpholino Oligomer Is Effective against Lethal Marburg Virus Infection in Cynomolgus Macaques.
Warren TK, Whitehouse CA, Wells J, Welch L, Charleston JS, Heald A, Nichols DK, Mattix ME, Palacios G, Kugleman JR, Iversen PL, Bavari S. Warren TK, et al. Among authors: iversen pl. PLoS Negl Trop Dis. 2016 Feb 22;10(2):e0004456. doi: 10.1371/journal.pntd.0004456. eCollection 2016 Feb. PLoS Negl Trop Dis. 2016. PMID: 26901785 Free PMC article.
209 results