Ivaska J - Search Results

1

⁶⁸Ga-DOTA-E[c(RGDfK)]₂ PET Imaging of SHARPIN-Regulated Integrin Activity in Mice.

Siitonen R, Peuhu E, Autio A, Liljenbäck H, Mattila E, Metsälä O, Käkelä M, Saanijoki T, Dijkgraaf I, Jalkanen S, Ivaska J, Roivainen A. Siitonen R, et al. Among authors: ivaska j. J Nucl Med. 2019 Oct;60(10):1380-1387. doi: 10.2967/jnumed.118.222026. Epub 2019 Mar 8. J Nucl Med. 2019. PMID: 30850498 Free PMC article.

2

Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP.

Mattila E, Pellinen T, Nevo J, Vuoriluoto K, Arjonen A, Ivaska J. Mattila E, et al. Among authors: ivaska j. Nat Cell Biol. 2005 Jan;7(1):78-85. doi: 10.1038/ncb1209. Epub 2004 Dec 12. Nat Cell Biol. 2005. PMID: 15592458

3

The protein tyrosine phosphatase TCPTP controls VEGFR2 signalling.

Mattila E, Auvinen K, Salmi M, Ivaska J. Mattila E, et al. Among authors: ivaska j. J Cell Sci. 2008 Nov 1;121(Pt 21):3570-80. doi: 10.1242/jcs.031898. Epub 2008 Oct 7. J Cell Sci. 2008. PMID: 18840653

4

CIP2A is associated with human breast cancer aggressivity.

Côme C, Laine A, Chanrion M, Edgren H, Mattila E, Liu X, Jonkers J, Ivaska J, Isola J, Darbon JM, Kallioniemi O, Thézenas S, Westermarck J. Côme C, et al. Among authors: ivaska j. Clin Cancer Res. 2009 Aug 15;15(16):5092-100. doi: 10.1158/1078-0432.CCR-08-3283. Epub 2009 Aug 11. Clin Cancer Res. 2009. PMID: 19671842

5

Mammary-derived growth inhibitor alters traffic of EGFR and induces a novel form of cetuximab resistance.

Nevo J, Mattila E, Pellinen T, Yamamoto DL, Sara H, Iljin K, Kallioniemi O, Bono P, Heikkilä P, Joensuu H, Wärri A, Ivaska J. Nevo J, et al. Among authors: ivaska j. Clin Cancer Res. 2009 Nov 1;15(21):6570-81. doi: 10.1158/1078-0432.CCR-09-0773. Epub 2009 Oct 13. Clin Cancer Res. 2009. PMID: 19825952

6

Inhibition of receptor tyrosine kinase signalling by small molecule agonist of T-cell protein tyrosine phosphatase.

Mattila E, Marttila H, Sahlberg N, Kohonen P, Tähtinen S, Halonen P, Perälä M, Ivaska J. Mattila E, et al. Among authors: ivaska j. BMC Cancer. 2010 Jan 7;10:7. doi: 10.1186/1471-2407-10-7. BMC Cancer. 2010. PMID: 20055993 Free PMC article.

7

High-throughput methods in identification of protein tyrosine phosphatase inhibitors and activators.

Mattila E, Ivaska J. Mattila E, et al. Among authors: ivaska j. Anticancer Agents Med Chem. 2011 Jan;11(1):141-50. doi: 10.2174/187152011794941235. Anticancer Agents Med Chem. 2011. PMID: 21288196 Review.

8

SHARPIN is an endogenous inhibitor of β1-integrin activation.

Rantala JK, Pouwels J, Pellinen T, Veltel S, Laasola P, Mattila E, Potter CS, Duffy T, Sundberg JP, Kallioniemi O, Askari JA, Humphries MJ, Parsons M, Salmi M, Ivaska J. Rantala JK, et al. Among authors: ivaska j. Nat Cell Biol. 2011 Sep 25;13(11):1315-24. doi: 10.1038/ncb2340. Nat Cell Biol. 2011. PMID: 21947080 Free PMC article.

9

Cytokinesis failure due to derailed integrin traffic induces aneuploidy and oncogenic transformation in vitro and in vivo.

Högnäs G, Tuomi S, Veltel S, Mattila E, Murumägi A, Edgren H, Kallioniemi O, Ivaska J. Högnäs G, et al. Among authors: ivaska j. Oncogene. 2012 Aug 2;31(31):3597-606. doi: 10.1038/onc.2011.527. Epub 2011 Nov 28. Oncogene. 2012. PMID: 22120710 Free PMC article.

10

Negative regulators of integrin activity.

Pouwels J, Nevo J, Pellinen T, Ylänne J, Ivaska J. Pouwels J, et al. Among authors: ivaska j. J Cell Sci. 2012 Jul 15;125(Pt 14):3271-80. doi: 10.1242/jcs.093641. Epub 2012 Jul 20. J Cell Sci. 2012. PMID: 22822081

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